Quantum-dot-tagged reduced graphene oxide nanocomposites for bright fluorescence bioimaging and photothermal therapy monitored in situ

Shang Hsiu Hu; Yu Wei Chen; Wen Ting Hung; I. Wei Chen; San-Yuan Chen

doi:10.1002/adma.201104070

Quantum-dot-tagged reduced graphene oxide nanocomposites for bright fluorescence bioimaging and photothermal therapy monitored in situ

Shang Hsiu Hu, Yu Wei Chen, Wen Ting Hung, I. Wei Chen, San-Yuan Chen^*

^*Corresponding author for this work

Department of Materials Science and Engineering

Research output: Contribution to journal › Article › peer-review

289 Scopus citations

Abstract

Quantum-dot-tagged reduced graphene oxide (QD-rGO) nanocomposites (left) internalized into targeted tumor cells display bright fluorescence from the QDs (right); by absorbing NIR radiation incident on the rGO and converting it into heat, they also cause simultaneous cell death and fluorescence reduction (bottom). The nanocomposite is thus capable of tumor imaging, photothermal therapy and in situ monitoring of treatment in progress.

Original language	English
Pages (from-to)	1748-1754
Number of pages	7
Journal	Advanced Materials
Volume	24
Issue number	13
DOIs	https://doi.org/10.1002/adma.201104070
State	Published - 3 Apr 2012

Keywords

fluorescence
graphene
nanocomposites
photothermal therapy
quantum dots

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10.1002/adma.201104070

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title = "Quantum-dot-tagged reduced graphene oxide nanocomposites for bright fluorescence bioimaging and photothermal therapy monitored in situ",

abstract = "Quantum-dot-tagged reduced graphene oxide (QD-rGO) nanocomposites (left) internalized into targeted tumor cells display bright fluorescence from the QDs (right); by absorbing NIR radiation incident on the rGO and converting it into heat, they also cause simultaneous cell death and fluorescence reduction (bottom). The nanocomposite is thus capable of tumor imaging, photothermal therapy and in situ monitoring of treatment in progress.",

keywords = "fluorescence, graphene, nanocomposites, photothermal therapy, quantum dots",

author = "Hu, {Shang Hsiu} and Chen, {Yu Wei} and Hung, {Wen Ting} and Chen, {I. Wei} and San-Yuan Chen",

year = "2012",

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AU - Hu, Shang Hsiu

AU - Chen, Yu Wei

AU - Hung, Wen Ting

AU - Chen, I. Wei

AU - Chen, San-Yuan

PY - 2012/4/3

Y1 - 2012/4/3

N2 - Quantum-dot-tagged reduced graphene oxide (QD-rGO) nanocomposites (left) internalized into targeted tumor cells display bright fluorescence from the QDs (right); by absorbing NIR radiation incident on the rGO and converting it into heat, they also cause simultaneous cell death and fluorescence reduction (bottom). The nanocomposite is thus capable of tumor imaging, photothermal therapy and in situ monitoring of treatment in progress.

AB - Quantum-dot-tagged reduced graphene oxide (QD-rGO) nanocomposites (left) internalized into targeted tumor cells display bright fluorescence from the QDs (right); by absorbing NIR radiation incident on the rGO and converting it into heat, they also cause simultaneous cell death and fluorescence reduction (bottom). The nanocomposite is thus capable of tumor imaging, photothermal therapy and in situ monitoring of treatment in progress.

KW - fluorescence

KW - graphene

KW - nanocomposites

KW - photothermal therapy

KW - quantum dots

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U2 - 10.1002/adma.201104070

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M3 - Article

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JO - Advanced Materials

JF - Advanced Materials

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ER -

Quantum-dot-tagged reduced graphene oxide nanocomposites for bright fluorescence bioimaging and photothermal therapy monitored in situ

Abstract

Keywords

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