Quantitative evaluation of age-related effects based on oxygenation dynamic signals during the wisconsin card sorting test

Yi Hua Huang; Chung Ming Chen; Yi Min Wang; Chia Wei Sun

doi:10.1109/JSTQE.2020.3019283

Quantitative evaluation of age-related effects based on oxygenation dynamic signals during the wisconsin card sorting test

Yi Hua Huang, Chung Ming Chen, Yi Min Wang, Chia Wei Sun^*

^*Corresponding author for this work

Department of Photonics

Research output: Contribution to journal › Article › peer-review

Abstract

The present study investigated age-related changes in the time-varying hemodynamics of the prefrontal cortex by using near-infrared spectroscopy (NIRS). NIRS is a real-time spectroscopic method used to measure functional hemodynamic responses related to neural activation in the brain. The prefrontal hemodynamic responses of 17 young adults and 21 elderly adults were monitored while they completed the Wisconsin card sorting test (WCST). The results revealed a slower activation pattern in oxyhemoglobin concentrations in the elderly group than in the young group. Furthermore, quantified results revealed timevarying trends in hemodynamic responses. The findings imply that age-related decline in hemodynamic responses may contribute to poorer performance during cognitive tasks.

Original language	English
Article number	7400106
Journal	IEEE Journal of Selected Topics in Quantum Electronics
Volume	27
Issue number	4
DOIs	https://doi.org/10.1109/JSTQE.2020.3019283
State	Published - 1 Jul 2020

Keywords

Brain age
Functional brain signal
Near-infrared spectroscopy
Wisconsin card sorting test

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10.1109/JSTQE.2020.3019283

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title = "Quantitative evaluation of age-related effects based on oxygenation dynamic signals during the wisconsin card sorting test",

abstract = "The present study investigated age-related changes in the time-varying hemodynamics of the prefrontal cortex by using near-infrared spectroscopy (NIRS). NIRS is a real-time spectroscopic method used to measure functional hemodynamic responses related to neural activation in the brain. The prefrontal hemodynamic responses of 17 young adults and 21 elderly adults were monitored while they completed the Wisconsin card sorting test (WCST). The results revealed a slower activation pattern in oxyhemoglobin concentrations in the elderly group than in the young group. Furthermore, quantified results revealed timevarying trends in hemodynamic responses. The findings imply that age-related decline in hemodynamic responses may contribute to poorer performance during cognitive tasks. ",

keywords = "Brain age, Functional brain signal, Near-infrared spectroscopy, Wisconsin card sorting test",

author = "Huang, {Yi Hua} and Chen, {Chung Ming} and Wang, {Yi Min} and Sun, {Chia Wei}",

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AU - Chen, Chung Ming

AU - Wang, Yi Min

AU - Sun, Chia Wei

PY - 2020/7/1

Y1 - 2020/7/1

N2 - The present study investigated age-related changes in the time-varying hemodynamics of the prefrontal cortex by using near-infrared spectroscopy (NIRS). NIRS is a real-time spectroscopic method used to measure functional hemodynamic responses related to neural activation in the brain. The prefrontal hemodynamic responses of 17 young adults and 21 elderly adults were monitored while they completed the Wisconsin card sorting test (WCST). The results revealed a slower activation pattern in oxyhemoglobin concentrations in the elderly group than in the young group. Furthermore, quantified results revealed timevarying trends in hemodynamic responses. The findings imply that age-related decline in hemodynamic responses may contribute to poorer performance during cognitive tasks.

AB - The present study investigated age-related changes in the time-varying hemodynamics of the prefrontal cortex by using near-infrared spectroscopy (NIRS). NIRS is a real-time spectroscopic method used to measure functional hemodynamic responses related to neural activation in the brain. The prefrontal hemodynamic responses of 17 young adults and 21 elderly adults were monitored while they completed the Wisconsin card sorting test (WCST). The results revealed a slower activation pattern in oxyhemoglobin concentrations in the elderly group than in the young group. Furthermore, quantified results revealed timevarying trends in hemodynamic responses. The findings imply that age-related decline in hemodynamic responses may contribute to poorer performance during cognitive tasks.

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Quantitative evaluation of age-related effects based on oxygenation dynamic signals during the wisconsin card sorting test

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