Psoriasis flare-ups following sorafenib therapy: A rare case

Ming Chun Hsu; Chih Chiang Chen

doi:10.1016/j.dsi.2016.01.004

Psoriasis flare-ups following sorafenib therapy: A rare case

Ming Chun Hsu, Chih Chiang Chen^*

^*Corresponding author for this work

Department of Dermatology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Sorafenib is a multikinase inhibitor that blocks tumor cell proliferation and angiogenesis. While adverse skin reactions occur in 90% of patients treated with angiogenesis inhibitors, only a few cases of psoriasiform eruption associated with sorafenib therapy have been reported. We report a rare case of sorafenib-related psoriasis that responded well to topical treatment and narrow-band UV-B phototherapy after discontinuation of sorafenib.

Original language	English
Pages (from-to)	148-150
Number of pages	3
Journal	Dermatologica Sinica
Volume	34
Issue number	3
DOIs	https://doi.org/10.1016/j.dsi.2016.01.004
State	Published - 1 Sep 2016

Keywords

kinase inhibitor
psoriasiform eruption
psoriasis
sorafenib

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10.1016/j.dsi.2016.01.004

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title = "Psoriasis flare-ups following sorafenib therapy: A rare case",

abstract = "Sorafenib is a multikinase inhibitor that blocks tumor cell proliferation and angiogenesis. While adverse skin reactions occur in 90% of patients treated with angiogenesis inhibitors, only a few cases of psoriasiform eruption associated with sorafenib therapy have been reported. We report a rare case of sorafenib-related psoriasis that responded well to topical treatment and narrow-band UV-B phototherapy after discontinuation of sorafenib.",

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AU - Chen, Chih Chiang

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N2 - Sorafenib is a multikinase inhibitor that blocks tumor cell proliferation and angiogenesis. While adverse skin reactions occur in 90% of patients treated with angiogenesis inhibitors, only a few cases of psoriasiform eruption associated with sorafenib therapy have been reported. We report a rare case of sorafenib-related psoriasis that responded well to topical treatment and narrow-band UV-B phototherapy after discontinuation of sorafenib.

AB - Sorafenib is a multikinase inhibitor that blocks tumor cell proliferation and angiogenesis. While adverse skin reactions occur in 90% of patients treated with angiogenesis inhibitors, only a few cases of psoriasiform eruption associated with sorafenib therapy have been reported. We report a rare case of sorafenib-related psoriasis that responded well to topical treatment and narrow-band UV-B phototherapy after discontinuation of sorafenib.

KW - kinase inhibitor

KW - psoriasiform eruption

KW - psoriasis

KW - sorafenib

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M3 - Article

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JO - Dermatologica Sinica

JF - Dermatologica Sinica

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ER -

Psoriasis flare-ups following sorafenib therapy: A rare case

Abstract

Keywords

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