Proteome-based diagnostics and prognosis of bladder transitional cell carcinoma

Ting Feng Wu*, Wan Ling Ku, Yeou Guang Tsay

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


More than 90% of bladder tumors are diagnosed as bladder transitional cell carcinoma and the majority of these lesions (70%) are diagnosed as superficial papillary lesions (stage pTa, T1). Recurrences are common to superficial tumors and few lesions will progress to a higher grade and/or stage and muscle invasion. Thus, diagnosing cancer at an early stage, predicting whether a tumor will recur and/or progress and identification of novel targets for cancer intervention, become the main focus of bladder cancer research. The purpose of this article is to briefly review what has been accomplished to date by using proteomic technology in order to develop a new strategy to resolve the problems of early detection, recurrence or therapeutic intervention.

Original languageEnglish
Pages (from-to)639-647
Number of pages9
JournalExpert Review of Proteomics
Issue number5
StatePublished - Oct 2007


  • Biomarker
  • Bladder transitional cell carcinoma
  • Proteomics


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