Prognostic indicators for survival after curative resection for patients with carcinoma of the stomach

Chew Wun Wu*, Mao Chih Hsieh, Su Shun Lo, Shyh Haw Tsay, Anna F.Y. Li, Wing Yiu Lui, Fang Ku P'Eng

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


This study aims to determine prognostic indicators among patient-, tumor-, and treatment-related factors of gastric cancer patients. A total of 510 patients who underwent curative gastric resection were studied. Univariate analysis of patient-related factors showed a significantly lower survival in patients with a history of obstruction, hypoalbuminemia, and anemia. Tumor-related factors including gross appearance, location, and size of tumor; depth of cancer invasion; level, number, and frequency of lymph node metastasis; stromal reaction and tumor growth pattern; and histological classfication all significantly affected survival. Surgical treatment related factors such as total or distal subtotal gastrectomy, extent of lymphadenectomy, and combined resection of adjacent organ(s) showed a statistically significant adverse influence on survival. Multivariate analysis identified only four tumor-related factors - number of metastatic lymph nodes, depth of cancer invasion, stromal reaction, and gross appearance of the tumor - as independently, affecting survival. These findings suggest that only four tumor-related factors were prognostic indicators in patients with gastric cancer.

Original languageEnglish
Pages (from-to)1265-1269
Number of pages5
JournalDigestive Diseases and Sciences
Issue number6
StatePublished - 1997


  • Gastrectomy
  • Gastric cancer
  • Prognosis
  • Survival


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