Production Enhancement of Reactive Oxygen and Nitrogen Species at Interface of Helium Plasma Jet and Agar

Chih Tung Liu, Ching Jung Wu, Zhi Hua Lin, Jane Yii Wu, Jong-Shinn Wu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Even though atmospheric-pressure plasma jet (APPJ) has been shown highly effective in many biomedical applications because of reactive oxygen/nitrogen species (RONS) generated in the discharge, free jet region, and at the interfacial region with the treated surface. However, most of the studies characterized APPJ only in either discharge or free jet region. In this paper, we measured optical emissions of RONS in free jet and plasma/surface interfacial regions of a helium-based dielectric barrier discharge APPJ. The results show that the emissions caused by RONS (nitric oxide, hydroxyl radical, and atomic oxygen) are enhanced 3-5 times at plasma/surface interfacial region as compared with those of free jet region. Some typical sterilization experiments using the current helium-based APPJ show that this helium-based APPJ effectively kills the oral bacteria (S. mutans) in 15 s, which was caused by the cell wall disruption. We believe that measuring the properties at plasma/surface interfacial region is more important than in the free jet region in characterizing APPJ for most realistic applications.

Original languageEnglish
Article number7546920
Pages (from-to)3112-3116
Number of pages5
JournalIEEE Transactions on Plasma Science
Issue number12
StatePublished - Dec 2016


  • Atmospheric-pressure plasma jet (APPJ)
  • plasma medicine
  • sterilization
  • surface enhancement


Dive into the research topics of 'Production Enhancement of Reactive Oxygen and Nitrogen Species at Interface of Helium Plasma Jet and Agar'. Together they form a unique fingerprint.

Cite this