Preparation and characterization of thermal-sensitive ferrofluids for drug delivery application

Ting Yu Liu; Shang Hsiu Hu; Sheng Hsiang Hu; Szu Ping Tsai; San-Yuan Chen

doi:10.1016/j.jmmm.2006.11.129

Preparation and characterization of thermal-sensitive ferrofluids for drug delivery application

Ting Yu Liu, Shang Hsiu Hu, Sheng Hsiang Hu, Szu Ping Tsai, San-Yuan Chen^*

^*Corresponding author for this work

Department of Materials Science and Engineering

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Novel thermal-sensitive ferrofluids (F127-ferrofluids) consisting of core-shell-type magnetic nanoparticles dispersed in Pluronic F127-containing aqueous solution were prepared. The core (magnet)-shell (Pluronic F127) nanoparticles were synthesized by in situ co-precipitation process, which were characterized using transmission electron microscope, X-ray diffraction and vibrating sample magnetometer. The F127-ferrofluids gelled above the lower critical solution temperatures (LCST) of approximately 23-28 °C, which were higher than that of pure Pluronic F127-fluids (21-25 °C). The increase in the LCST of the F127 ferrofluids may be attributed to a result of a physical interaction between the F127 molecules and the core-shell magnetic nanoparticles.

Original language	English
Pages (from-to)	2850-2852
Number of pages	3
Journal	Journal of Magnetism and Magnetic Materials
Volume	310
Issue number	2 SUPPL. PART 3
DOIs	https://doi.org/10.1016/j.jmmm.2006.11.129
State	Published - 1 Mar 2007

Keywords

Core-shell
Drug delivery
Ferrofluid
Magnetic nanoparticle
Pluronic F127
Thermal sensitive

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10.1016/j.jmmm.2006.11.129

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title = "Preparation and characterization of thermal-sensitive ferrofluids for drug delivery application",

abstract = "Novel thermal-sensitive ferrofluids (F127-ferrofluids) consisting of core-shell-type magnetic nanoparticles dispersed in Pluronic F127-containing aqueous solution were prepared. The core (magnet)-shell (Pluronic F127) nanoparticles were synthesized by in situ co-precipitation process, which were characterized using transmission electron microscope, X-ray diffraction and vibrating sample magnetometer. The F127-ferrofluids gelled above the lower critical solution temperatures (LCST) of approximately 23-28 °C, which were higher than that of pure Pluronic F127-fluids (21-25 °C). The increase in the LCST of the F127 ferrofluids may be attributed to a result of a physical interaction between the F127 molecules and the core-shell magnetic nanoparticles.",

keywords = "Core-shell, Drug delivery, Ferrofluid, Magnetic nanoparticle, Pluronic F127, Thermal sensitive",

author = "Liu, {Ting Yu} and Hu, {Shang Hsiu} and Hu, {Sheng Hsiang} and Tsai, {Szu Ping} and San-Yuan Chen",

year = "2007",

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doi = "10.1016/j.jmmm.2006.11.129",

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T1 - Preparation and characterization of thermal-sensitive ferrofluids for drug delivery application

AU - Liu, Ting Yu

AU - Hu, Shang Hsiu

AU - Hu, Sheng Hsiang

AU - Tsai, Szu Ping

AU - Chen, San-Yuan

PY - 2007/3/1

Y1 - 2007/3/1

N2 - Novel thermal-sensitive ferrofluids (F127-ferrofluids) consisting of core-shell-type magnetic nanoparticles dispersed in Pluronic F127-containing aqueous solution were prepared. The core (magnet)-shell (Pluronic F127) nanoparticles were synthesized by in situ co-precipitation process, which were characterized using transmission electron microscope, X-ray diffraction and vibrating sample magnetometer. The F127-ferrofluids gelled above the lower critical solution temperatures (LCST) of approximately 23-28 °C, which were higher than that of pure Pluronic F127-fluids (21-25 °C). The increase in the LCST of the F127 ferrofluids may be attributed to a result of a physical interaction between the F127 molecules and the core-shell magnetic nanoparticles.

AB - Novel thermal-sensitive ferrofluids (F127-ferrofluids) consisting of core-shell-type magnetic nanoparticles dispersed in Pluronic F127-containing aqueous solution were prepared. The core (magnet)-shell (Pluronic F127) nanoparticles were synthesized by in situ co-precipitation process, which were characterized using transmission electron microscope, X-ray diffraction and vibrating sample magnetometer. The F127-ferrofluids gelled above the lower critical solution temperatures (LCST) of approximately 23-28 °C, which were higher than that of pure Pluronic F127-fluids (21-25 °C). The increase in the LCST of the F127 ferrofluids may be attributed to a result of a physical interaction between the F127 molecules and the core-shell magnetic nanoparticles.

KW - Core-shell

KW - Drug delivery

KW - Ferrofluid

KW - Magnetic nanoparticle

KW - Pluronic F127

KW - Thermal sensitive

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U2 - 10.1016/j.jmmm.2006.11.129

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SN - 0304-8853

VL - 310

SP - 2850

EP - 2852

JO - Journal of Magnetism and Magnetic Materials

JF - Journal of Magnetism and Magnetic Materials

IS - 2 SUPPL. PART 3

ER -

Preparation and characterization of thermal-sensitive ferrofluids for drug delivery application

Abstract

Keywords

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