Portable LED-induced autofluorescence imager with a probe of L shape for oral cancer diagnosis

Ting Wei Huang, Yu Cheng Lee, Nai Lun Cheng, Yung Jhe Yan, Hou Chi Chiang, Jin-Chern Chiou, Yang-Mang Ou

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations


The difference of spectral distribution between lesions of epithelial cells and normal cells after excited fluorescence is one of methods for the cancer diagnosis. In our previous work, we developed a portable LED Induced autofluorescence (LIAF) imager contained the multiple wavelength of LED excitation light and multiple filters to capture ex-vivo oral tissue autofluorescence images. Our portable system for detection of oral cancer has a probe in front of the lens for fixing the object distance. The shape of the probe is cone, and it is not convenient for doctor to capture the oral image under an appropriate view angle in front of the probe. Therefore, a probe of L shape containing a mirror is proposed for doctors to capture the images with the right angles, and the subjects do not need to open their mouse constrainedly. Besides, a glass plate is placed in probe to prevent the liquid entering in the body, but the light reflected from the glass plate directly causes the light spots inside the images. We set the glass plate in front of LED to avoiding the light spots. When the distance between the glasses plate and the LED model plane is less than the critical value, then we can prevent the light spots caused from the glasses plate. The experiments show that the image captured with the new probe that the glasses plate placed in the back-end of the probe has no light spots inside the image.

Original languageEnglish
Title of host publicationMedical Applications of Radiation Detectors V
EditorsLars R. Furenlid, H. Bradford Barber, Hans N. Roehrig
ISBN (Electronic)9781628417609
StatePublished - 1 Jan 2015
EventMedical Applications of Radiation Detectors V - San Diego, United States
Duration: 12 Aug 201513 Aug 2015

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X


ConferenceMedical Applications of Radiation Detectors V
Country/TerritoryUnited States
CitySan Diego


  • Autofluorescence
  • LED
  • light spots
  • oral cancer
  • probe


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