Polysaccharide-lecithin reverse micelles with enzyme-degradable triglyceride shell for overcoming tumor multidrug resistance

Chia Wei Su; San-Yuan Chen; Dean-Mo LIu

doi:10.1039/c3cc40836a

Polysaccharide-lecithin reverse micelles with enzyme-degradable triglyceride shell for overcoming tumor multidrug resistance

Chia Wei Su, San-Yuan Chen^*, Dean-Mo LIu

^*Corresponding author for this work

Department of Materials Science and Engineering

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

A newly-designed drug carrier with enzyme-triggered release behavior and the ability to circumvent multidrug resistance was successfully developed. By optimizing the ratio of lecithin and polysaccharide in reverse micelles, encapsulation efficiency and encapsulation stability can be significantly improved.

Original language	English
Pages (from-to)	3772-3774
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	36
DOIs	https://doi.org/10.1039/c3cc40836a
State	Published - 9 Apr 2013

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title = "Polysaccharide-lecithin reverse micelles with enzyme-degradable triglyceride shell for overcoming tumor multidrug resistance",

abstract = "A newly-designed drug carrier with enzyme-triggered release behavior and the ability to circumvent multidrug resistance was successfully developed. By optimizing the ratio of lecithin and polysaccharide in reverse micelles, encapsulation efficiency and encapsulation stability can be significantly improved.",

author = "Su, {Chia Wei} and San-Yuan Chen and Dean-Mo LIu",

year = "2013",

month = apr,

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doi = "10.1039/c3cc40836a",

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T1 - Polysaccharide-lecithin reverse micelles with enzyme-degradable triglyceride shell for overcoming tumor multidrug resistance

AU - Su, Chia Wei

AU - Chen, San-Yuan

AU - LIu, Dean-Mo

PY - 2013/4/9

Y1 - 2013/4/9

N2 - A newly-designed drug carrier with enzyme-triggered release behavior and the ability to circumvent multidrug resistance was successfully developed. By optimizing the ratio of lecithin and polysaccharide in reverse micelles, encapsulation efficiency and encapsulation stability can be significantly improved.

AB - A newly-designed drug carrier with enzyme-triggered release behavior and the ability to circumvent multidrug resistance was successfully developed. By optimizing the ratio of lecithin and polysaccharide in reverse micelles, encapsulation efficiency and encapsulation stability can be significantly improved.

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U2 - 10.1039/c3cc40836a

DO - 10.1039/c3cc40836a

M3 - Article

C2 - 23536208

AN - SCOPUS:84876157106

SN - 1359-7345

VL - 49

SP - 3772

EP - 3774

JO - Chemical Communications

JF - Chemical Communications

IS - 36

ER -

Polysaccharide-lecithin reverse micelles with enzyme-degradable triglyceride shell for overcoming tumor multidrug resistance

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