TY - GEN
T1 - Optical Technique for Estimating Cerebral Perfusion Pressure
AU - Chen, Chang Ting
AU - Liao, Yi Chien
AU - Lai, Chien Fu
AU - Lin, Bor-Shyh
AU - Wang, Che Chuan
AU - Kuo, Jinn Rung
PY - 2016/2/19
Y1 - 2016/2/19
N2 - It is important to avoid secondary brain injury after Traumatic brain injury (TBI) in clinical. Cerebral perfusion pressure (CPP) is associated with blood flow into the brain, and indirectly reflects the cerebral ischemia and oxygenation. However, it is invasive and is inconvenient for continuous monitoring. Recently, near infrared spectroscopy (NIRS) has been widely applied for monitoring cerebral ischemia and hypoxia. In this study, we developed a wireless NIRS system to monitor rat's brain in different impact strengths of trauma. Commercial ICP and MAP devices were also used to compare with NIRS parameters under TBI. The Experimental results show all of δCPP, δ [HbO2], δ [HBT], and δ [HbR] were inversely proportional to the increased impact strengths, and the correlations between δCPP, and δ [HbO2] and δ [HBT] are high. Hence NIRS system may be useful for estimating the level of cerebral perfusion pressure non-invasively.
AB - It is important to avoid secondary brain injury after Traumatic brain injury (TBI) in clinical. Cerebral perfusion pressure (CPP) is associated with blood flow into the brain, and indirectly reflects the cerebral ischemia and oxygenation. However, it is invasive and is inconvenient for continuous monitoring. Recently, near infrared spectroscopy (NIRS) has been widely applied for monitoring cerebral ischemia and hypoxia. In this study, we developed a wireless NIRS system to monitor rat's brain in different impact strengths of trauma. Commercial ICP and MAP devices were also used to compare with NIRS parameters under TBI. The Experimental results show all of δCPP, δ [HbO2], δ [HBT], and δ [HbR] were inversely proportional to the increased impact strengths, and the correlations between δCPP, and δ [HbO2] and δ [HBT] are high. Hence NIRS system may be useful for estimating the level of cerebral perfusion pressure non-invasively.
KW - Cerebral perfusion pressure
KW - Near-infrared spectroscopy
KW - Traumatic brain injury
UR - http://www.scopus.com/inward/record.url?scp=84963930683&partnerID=8YFLogxK
U2 - 10.1109/IIH-MSP.2015.15
DO - 10.1109/IIH-MSP.2015.15
M3 - Conference contribution
AN - SCOPUS:84963930683
T3 - Proceedings - 2015 International Conference on Intelligent Information Hiding and Multimedia Signal Processing, IIH-MSP 2015
SP - 57
EP - 59
BT - Proceedings - 2015 International Conference on Intelligent Information Hiding and Multimedia Signal Processing, IIH-MSP 2015
A2 - Pan, Jeng-Shyang
A2 - Yang, Ching-Yu
A2 - Huang, Hsiang-Cheh
A2 - Lee, Ivan
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 11th International Conference on Intelligent Information Hiding and Multimedia Signal Processing, IIH-MSP 2015
Y2 - 23 September 2015 through 25 September 2015
ER -