Optical Technique for Estimating Cerebral Perfusion Pressure

Chang Ting Chen, Yi Chien Liao, Chien Fu Lai, Bor-Shyh Lin, Che Chuan Wang, Jinn Rung Kuo

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

It is important to avoid secondary brain injury after Traumatic brain injury (TBI) in clinical. Cerebral perfusion pressure (CPP) is associated with blood flow into the brain, and indirectly reflects the cerebral ischemia and oxygenation. However, it is invasive and is inconvenient for continuous monitoring. Recently, near infrared spectroscopy (NIRS) has been widely applied for monitoring cerebral ischemia and hypoxia. In this study, we developed a wireless NIRS system to monitor rat's brain in different impact strengths of trauma. Commercial ICP and MAP devices were also used to compare with NIRS parameters under TBI. The Experimental results show all of δCPP, δ [HbO2], δ [HBT], and δ [HbR] were inversely proportional to the increased impact strengths, and the correlations between δCPP, and δ [HbO2] and δ [HBT] are high. Hence NIRS system may be useful for estimating the level of cerebral perfusion pressure non-invasively.

Original languageEnglish
Title of host publicationProceedings - 2015 International Conference on Intelligent Information Hiding and Multimedia Signal Processing, IIH-MSP 2015
EditorsJeng-Shyang Pan, Ching-Yu Yang, Hsiang-Cheh Huang, Ivan Lee
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages57-59
Number of pages3
ISBN (Electronic)9781509001880
DOIs
StatePublished - 19 Feb 2016
Event11th International Conference on Intelligent Information Hiding and Multimedia Signal Processing, IIH-MSP 2015 - Adelaide, Australia
Duration: 23 Sep 201525 Sep 2015

Publication series

NameProceedings - 2015 International Conference on Intelligent Information Hiding and Multimedia Signal Processing, IIH-MSP 2015

Conference

Conference11th International Conference on Intelligent Information Hiding and Multimedia Signal Processing, IIH-MSP 2015
Country/TerritoryAustralia
CityAdelaide
Period23/09/1525/09/15

Keywords

  • Cerebral perfusion pressure
  • Near-infrared spectroscopy
  • Traumatic brain injury

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