One-pot synthesis of copper nanoconjugate materials as luminescent sensor for Fe3+ and I− detection in human urine sample

Yu Ting Tai; Turibius Simon; Yun Yi Chu; Fu-Hsiang Ko

doi:10.1016/j.sbsr.2019.100319

One-pot synthesis of copper nanoconjugate materials as luminescent sensor for Fe³⁺ and I⁻ detection in human urine sample

Yu Ting Tai, Turibius Simon, Yun Yi Chu, Fu-Hsiang Ko^*

^*Corresponding author for this work

Department of Materials Science and Engineering

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A simple synthetic approach of water-soluble and stable fluorescent copper nanoclusters (Cu NCs) at room temperature was proposed. The cysteamine functionalized nanoconjugate materials (CA-Cu NCs) exhibited variety of exceptional properties, including good water-solubility, photostability, low cytotoxicity and acting as an excellent cell imaging probe. Based on the electron transfer and aggregation induced fluorescence quenching mechanism, CA-Cu NCs were utilized in the selective determination of ferric (Fe³⁺) and iodide (I⁻) ions. The detection limits of Fe³⁺ and I⁻ ions were calculated as 423 nM and 2.02 μM, which are lower than the maximum level of Fe³⁺ and I⁻ ions, allowed in drinking water by the U.S. Environmental Protection Agency. The assay method of paper strip was also successfully applied for the detection of Fe³⁺ and I⁻ ions in live cells and human urine.

Original language	English
Article number	100319
Journal	Sensing and Bio-Sensing Research
Volume	27
DOIs	https://doi.org/10.1016/j.sbsr.2019.100319
State	Published - Feb 2020

Keywords

Cell imaging
Copper nanoclusters
Cysteamine
Fe3+ and I- detection
Fluorescent assay
Paper strip

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10.1016/j.sbsr.2019.100319

Cite this

@article{02066fb07a9545128b293f8135ccf9bb,

title = "One-pot synthesis of copper nanoconjugate materials as luminescent sensor for Fe3+ and I− detection in human urine sample",

abstract = "A simple synthetic approach of water-soluble and stable fluorescent copper nanoclusters (Cu NCs) at room temperature was proposed. The cysteamine functionalized nanoconjugate materials (CA-Cu NCs) exhibited variety of exceptional properties, including good water-solubility, photostability, low cytotoxicity and acting as an excellent cell imaging probe. Based on the electron transfer and aggregation induced fluorescence quenching mechanism, CA-Cu NCs were utilized in the selective determination of ferric (Fe3+) and iodide (I−) ions. The detection limits of Fe3+ and I− ions were calculated as 423 nM and 2.02 μM, which are lower than the maximum level of Fe3+ and I− ions, allowed in drinking water by the U.S. Environmental Protection Agency. The assay method of paper strip was also successfully applied for the detection of Fe3+ and I− ions in live cells and human urine.",

keywords = "Cell imaging, Copper nanoclusters, Cysteamine, Fe3+ and I- detection, Fluorescent assay, Paper strip",

author = "Tai, {Yu Ting} and Turibius Simon and Chu, {Yun Yi} and Fu-Hsiang Ko",

note = "Publisher Copyright: {\textcopyright} 2019 The Authors",

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T1 - One-pot synthesis of copper nanoconjugate materials as luminescent sensor for Fe3+ and I− detection in human urine sample

AU - Tai, Yu Ting

AU - Simon, Turibius

AU - Chu, Yun Yi

AU - Ko, Fu-Hsiang

PY - 2020/2

Y1 - 2020/2

N2 - A simple synthetic approach of water-soluble and stable fluorescent copper nanoclusters (Cu NCs) at room temperature was proposed. The cysteamine functionalized nanoconjugate materials (CA-Cu NCs) exhibited variety of exceptional properties, including good water-solubility, photostability, low cytotoxicity and acting as an excellent cell imaging probe. Based on the electron transfer and aggregation induced fluorescence quenching mechanism, CA-Cu NCs were utilized in the selective determination of ferric (Fe3+) and iodide (I−) ions. The detection limits of Fe3+ and I− ions were calculated as 423 nM and 2.02 μM, which are lower than the maximum level of Fe3+ and I− ions, allowed in drinking water by the U.S. Environmental Protection Agency. The assay method of paper strip was also successfully applied for the detection of Fe3+ and I− ions in live cells and human urine.

AB - A simple synthetic approach of water-soluble and stable fluorescent copper nanoclusters (Cu NCs) at room temperature was proposed. The cysteamine functionalized nanoconjugate materials (CA-Cu NCs) exhibited variety of exceptional properties, including good water-solubility, photostability, low cytotoxicity and acting as an excellent cell imaging probe. Based on the electron transfer and aggregation induced fluorescence quenching mechanism, CA-Cu NCs were utilized in the selective determination of ferric (Fe3+) and iodide (I−) ions. The detection limits of Fe3+ and I− ions were calculated as 423 nM and 2.02 μM, which are lower than the maximum level of Fe3+ and I− ions, allowed in drinking water by the U.S. Environmental Protection Agency. The assay method of paper strip was also successfully applied for the detection of Fe3+ and I− ions in live cells and human urine.

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KW - Copper nanoclusters

KW - Cysteamine

KW - Fe3+ and I- detection

KW - Fluorescent assay

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