Odor identification and cognitive function in the beaver dam offspring study

Carla R. Schubert; Karen J. Cruickshanks; Mary E. Fischer; Guan-Hua Huang; Ronald Klein; Nathan Pankratz; Wenjun Zhong; David M. Nondahl

doi:10.1080/13803395.2013.809701

Odor identification and cognitive function in the beaver dam offspring study

Carla R. Schubert^*, Karen J. Cruickshanks, Mary E. Fischer, Guan-Hua Huang, Ronald Klein, Nathan Pankratz, Wenjun Zhong, David M. Nondahl

^*Corresponding author for this work

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31 Scopus citations

Abstract

Olfactory impairment is associated with cognitive impairment in older adults but less is known about the association of olfactory impairment and cognitive function in middle-aged adults. The association between olfactory impairment and cognitive function tests of attention, processing speed, and executive and psychomotor function was explored in 2837 participants (21-84 years; mean age 49 years) in the Beaver Dam Offspring Study. Among middle-aged participants (aged 35-64 years), those with impairment on an odor identification test took significantly longer to complete the Trail Making Test (TMT-A and TMT-B) and the Grooved Peg Board (GPB) test, than those without olfactory impairment in regression models adjusted for multiple factors. Similar results were found for the TMT-A and TMT-B, but not the GPB, in the whole cohort. Olfactory impairment was associated with poorer performance on cognitive function tests in a primarily middle-aged cohort.

Original language	English
Pages (from-to)	669-676
Number of pages	8
Journal	Journal of Clinical and Experimental Neuropsychology
Volume	35
Issue number	7
DOIs	https://doi.org/10.1080/13803395.2013.809701
State	Published - 19 Aug 2013

Keywords

Cognitive function
Epidemiology
Executive function
Odor identification
Olfaction

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10.1080/13803395.2013.809701

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title = "Odor identification and cognitive function in the beaver dam offspring study",

abstract = "Olfactory impairment is associated with cognitive impairment in older adults but less is known about the association of olfactory impairment and cognitive function in middle-aged adults. The association between olfactory impairment and cognitive function tests of attention, processing speed, and executive and psychomotor function was explored in 2837 participants (21-84 years; mean age 49 years) in the Beaver Dam Offspring Study. Among middle-aged participants (aged 35-64 years), those with impairment on an odor identification test took significantly longer to complete the Trail Making Test (TMT-A and TMT-B) and the Grooved Peg Board (GPB) test, than those without olfactory impairment in regression models adjusted for multiple factors. Similar results were found for the TMT-A and TMT-B, but not the GPB, in the whole cohort. Olfactory impairment was associated with poorer performance on cognitive function tests in a primarily middle-aged cohort.",

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AU - Cruickshanks, Karen J.

AU - Fischer, Mary E.

AU - Huang, Guan-Hua

AU - Klein, Ronald

AU - Pankratz, Nathan

AU - Zhong, Wenjun

AU - Nondahl, David M.

PY - 2013/8/19

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N2 - Olfactory impairment is associated with cognitive impairment in older adults but less is known about the association of olfactory impairment and cognitive function in middle-aged adults. The association between olfactory impairment and cognitive function tests of attention, processing speed, and executive and psychomotor function was explored in 2837 participants (21-84 years; mean age 49 years) in the Beaver Dam Offspring Study. Among middle-aged participants (aged 35-64 years), those with impairment on an odor identification test took significantly longer to complete the Trail Making Test (TMT-A and TMT-B) and the Grooved Peg Board (GPB) test, than those without olfactory impairment in regression models adjusted for multiple factors. Similar results were found for the TMT-A and TMT-B, but not the GPB, in the whole cohort. Olfactory impairment was associated with poorer performance on cognitive function tests in a primarily middle-aged cohort.

AB - Olfactory impairment is associated with cognitive impairment in older adults but less is known about the association of olfactory impairment and cognitive function in middle-aged adults. The association between olfactory impairment and cognitive function tests of attention, processing speed, and executive and psychomotor function was explored in 2837 participants (21-84 years; mean age 49 years) in the Beaver Dam Offspring Study. Among middle-aged participants (aged 35-64 years), those with impairment on an odor identification test took significantly longer to complete the Trail Making Test (TMT-A and TMT-B) and the Grooved Peg Board (GPB) test, than those without olfactory impairment in regression models adjusted for multiple factors. Similar results were found for the TMT-A and TMT-B, but not the GPB, in the whole cohort. Olfactory impairment was associated with poorer performance on cognitive function tests in a primarily middle-aged cohort.

KW - Cognitive function

KW - Epidemiology

KW - Executive function

KW - Odor identification

KW - Olfaction

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ER -

Odor identification and cognitive function in the beaver dam offspring study

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Keywords

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