Obeticholic acid ameliorates hepatorenal syndrome in ascitic cirrhotic rats by down-regulating the renal 8-iso-PGF2α-activated COX-TXA2pathway

Yu Lien Tsai, Chih Wei Liu, Chien Fu Hsu, Chia Chang Huang, Ming Wei Lin, Shiang Fen Huang, Tzu Hao Li, Kuei Chuan Lee, Yun Cheng Hsieh, Ying Ying Yang*, Tzung Yan Lee, Hsuan Miao Liu, Yi Hsiang Huang, Ming Chih Hou, Han Chieh Lin

*Corresponding author for this work

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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science