NLRP3 Inflammasome Activates Endothelial-to-Mesenchymal Transition via Focal Adhesion Kinase Pathway in Bleomycin-Induced Pulmonary Fibrosis

Keyphrases

• Bleomycin-induced Pulmonary Fibrosis 100%
• Focal Adhesion Kinase 100%
• Kinase Cascade 100%
• NLRP3 Inflammasome 100%
• Endothelial-to-mesenchymal Transition (EndMT) 100%
• Bleomycin 37%
• Pulmonary Fibrosis 25%
• Lung Specimen 25%
• Western Blotting 12%
• Immunofluorescence 12%
• Poor Clinical Outcomes 12%
• Immunohistochemical Staining 12%
• Vimentin 12%
• C57BL 12%
• Detailed Mechanism 12%
• Enzyme-linked Immunosorbent Assay (ELISA) 12%
• In Vitro Study 12%
• Masson's Trichrome Stain 12%
• Lung Inflammation 12%
• Antifibrotic 12%
• Lung Fibrosis 12%
• α-smooth muscle Actin (α-SMA) 12%
• Nucleotide-binding Domain 12%
• Vascular Endothelial-cadherin 12%
• Idiopathic Pulmonary Fibrosis 12%
• Leucine-rich Repeat 12%
• Intratracheal Injection 12%
• Human Pulmonary Microvascular Endothelial Cells 12%
• Pyrin Domain Containing 3 12%
• Caspase-1 Inhibitor 12%
• Inflammasome Inhibition 12%

Medicine and Dentistry

• NLRP3 Inflammasome 100%
• Focal Adhesion Kinase 100%
• Bleomycin-Induced Pulmonary Fibrosis 100%
• Janus Kinase 1 100%
• Pulmonary Fibrosis 37%
• Bleomycin 37%
• In Vitro 25%
• Lung 25%
• Endothelial Cell 12%
• Western Blot 12%
• Idiopathic Pulmonary Fibrosis 12%
• Receptor 12%
• Enzyme Linked Immunosorbent Assay 12%
• C57BL/6 12%
• Vimentin 12%
• Immunofluorescence 12%
• Vascular Endothelial Cadherin 12%
• Pyrin Domain 12%
• Pneumonia 12%
• Leucine 12%
• Alpha Smooth Muscle Actin 12%
• Trichrome 12%
• Intratracheal Drug Administration 12%
• Interleukin 1beta Converting Enzyme 12%