TY - JOUR
T1 - Neuropathic Pain Affects Quality of Life in Breast Cancer Survivors with Chemotherapy-Induced Peripheral Neuropathy
AU - Jheng, You Wun
AU - Chan, Ya Ning
AU - Wu, Chih Jung
AU - Lin, Ming Wei
AU - Tseng, Ling Ming
AU - Wang, Ya Jung
N1 - Publisher Copyright:
© 2024 American Society for Pain Management Nursing
PY - 2024/6
Y1 - 2024/6
N2 - Background: Despite the significant impact of chemotherapy-induced peripheral neuropathy on the quality of life for breast cancer survivors, there is a notable lack of comprehensive research. Therefore, a crucial need exists for further systematic investigation and inquiry into this matter. Aims: This study examined predictors of quality of life in breast cancer survivors with chemotherapy-induced peripheral neuropathy. Design: A cross-sectional, correlational design. Settings: This study was conducted at a medical center in northern Taiwan and a teaching hospital in northeastern Taiwan. Participants/Subjects: One hundred and thirty adult women with breast cancer, who have undergone chemotherapy and obtained a Total Neuropathy Scale-Clinical Version score>0, were enrolled. Methods: Neuropathic pain, sleep disturbances, depression, and quality of life were evaluated using multiple regression analysis to identify quality of life predictors. Clinical importance was established using the minimally important difference of Functional Assessment of Cancer Therapy-Breast. Results: The study indicated that improving depression (B = –10.87, p < .001) and neuropathic pain (B = –8.33, p = .004) may enhance the quality of life of breast cancer survivors with chemotherapy-induced peripheral neuropathy. Moreover, the individual's marital status and family history of breast cancer were identified as predictive factors. Conclusions: This study illuminates quality of life determinants for breast cancer survivors with chemotherapy-induced peripheral neuropathy, advocating comprehensive care and addressing depression and neuropathic pain for better outcomes.
AB - Background: Despite the significant impact of chemotherapy-induced peripheral neuropathy on the quality of life for breast cancer survivors, there is a notable lack of comprehensive research. Therefore, a crucial need exists for further systematic investigation and inquiry into this matter. Aims: This study examined predictors of quality of life in breast cancer survivors with chemotherapy-induced peripheral neuropathy. Design: A cross-sectional, correlational design. Settings: This study was conducted at a medical center in northern Taiwan and a teaching hospital in northeastern Taiwan. Participants/Subjects: One hundred and thirty adult women with breast cancer, who have undergone chemotherapy and obtained a Total Neuropathy Scale-Clinical Version score>0, were enrolled. Methods: Neuropathic pain, sleep disturbances, depression, and quality of life were evaluated using multiple regression analysis to identify quality of life predictors. Clinical importance was established using the minimally important difference of Functional Assessment of Cancer Therapy-Breast. Results: The study indicated that improving depression (B = –10.87, p < .001) and neuropathic pain (B = –8.33, p = .004) may enhance the quality of life of breast cancer survivors with chemotherapy-induced peripheral neuropathy. Moreover, the individual's marital status and family history of breast cancer were identified as predictive factors. Conclusions: This study illuminates quality of life determinants for breast cancer survivors with chemotherapy-induced peripheral neuropathy, advocating comprehensive care and addressing depression and neuropathic pain for better outcomes.
UR - http://www.scopus.com/inward/record.url?scp=85184182025&partnerID=8YFLogxK
U2 - 10.1016/j.pmn.2023.12.013
DO - 10.1016/j.pmn.2023.12.013
M3 - Article
C2 - 38278750
AN - SCOPUS:85184182025
SN - 1524-9042
VL - 25
SP - 308
EP - 315
JO - Pain Management Nursing
JF - Pain Management Nursing
IS - 3
ER -