Near-Infrared-II Semiconducting Polymer Dots for Deep-tissue Fluorescence Imaging

Nidhi Gupta, Yang Hsiang Chan*, Sampa Saha, Ming Ho Liu

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations


Fluorescence imaging, particularly in the NIR-II region (1000–1700 nm), has become an unprecedented tool for deep-tissue in vivo imaging. Among the fluorescent nanoprobes, semiconducting polymer nanoparticles (Pdots) appear to be a promising agent because of their tunable optical and photophysical properties, ultrahigh brightness, minimal autofluorescence, narrow-size distribution, and low cytotoxicity. This review elucidates the recent advances in Pdots for deep-tissue fluorescence imaging and the facing future translation to clinical use.

Original languageEnglish
Pages (from-to)175-184
Number of pages10
JournalChemistry - An Asian Journal
Issue number3
StatePublished - 1 Feb 2021


  • deep-tissue
  • fluorescence
  • NIR-II
  • optical properties
  • polymer dots


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