Near-Infrared-II Semiconducting Polymer Dots for Deep-tissue Fluorescence Imaging

Nidhi Gupta; Yang Hsiang Chan; Sampa Saha; Ming Ho Liu

doi:10.1002/asia.202001348

Near-Infrared-II Semiconducting Polymer Dots for Deep-tissue Fluorescence Imaging

Nidhi Gupta, Yang Hsiang Chan^*, Sampa Saha, Ming Ho Liu

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

23 Scopus citations

Abstract

Fluorescence imaging, particularly in the NIR-II region (1000–1700 nm), has become an unprecedented tool for deep-tissue in vivo imaging. Among the fluorescent nanoprobes, semiconducting polymer nanoparticles (Pdots) appear to be a promising agent because of their tunable optical and photophysical properties, ultrahigh brightness, minimal autofluorescence, narrow-size distribution, and low cytotoxicity. This review elucidates the recent advances in Pdots for deep-tissue fluorescence imaging and the facing future translation to clinical use.

Original language	English
Pages (from-to)	175-184
Number of pages	10
Journal	Chemistry - An Asian Journal
Volume	16
Issue number	3
DOIs	https://doi.org/10.1002/asia.202001348
State	Published - 1 Feb 2021

Keywords

deep-tissue
fluorescence
NIR-II
optical properties
polymer dots

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title = "Near-Infrared-II Semiconducting Polymer Dots for Deep-tissue Fluorescence Imaging",

abstract = "Fluorescence imaging, particularly in the NIR-II region (1000–1700 nm), has become an unprecedented tool for deep-tissue in vivo imaging. Among the fluorescent nanoprobes, semiconducting polymer nanoparticles (Pdots) appear to be a promising agent because of their tunable optical and photophysical properties, ultrahigh brightness, minimal autofluorescence, narrow-size distribution, and low cytotoxicity. This review elucidates the recent advances in Pdots for deep-tissue fluorescence imaging and the facing future translation to clinical use.",

keywords = "deep-tissue, fluorescence, NIR-II, optical properties, polymer dots",

author = "Nidhi Gupta and Chan, {Yang Hsiang} and Sampa Saha and Liu, {Ming Ho}",

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AU - Gupta, Nidhi

AU - Chan, Yang Hsiang

AU - Saha, Sampa

AU - Liu, Ming Ho

PY - 2021/2/1

Y1 - 2021/2/1

N2 - Fluorescence imaging, particularly in the NIR-II region (1000–1700 nm), has become an unprecedented tool for deep-tissue in vivo imaging. Among the fluorescent nanoprobes, semiconducting polymer nanoparticles (Pdots) appear to be a promising agent because of their tunable optical and photophysical properties, ultrahigh brightness, minimal autofluorescence, narrow-size distribution, and low cytotoxicity. This review elucidates the recent advances in Pdots for deep-tissue fluorescence imaging and the facing future translation to clinical use.

AB - Fluorescence imaging, particularly in the NIR-II region (1000–1700 nm), has become an unprecedented tool for deep-tissue in vivo imaging. Among the fluorescent nanoprobes, semiconducting polymer nanoparticles (Pdots) appear to be a promising agent because of their tunable optical and photophysical properties, ultrahigh brightness, minimal autofluorescence, narrow-size distribution, and low cytotoxicity. This review elucidates the recent advances in Pdots for deep-tissue fluorescence imaging and the facing future translation to clinical use.

KW - deep-tissue

KW - fluorescence

KW - NIR-II

KW - optical properties

KW - polymer dots

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JF - Chemistry - An Asian Journal

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ER -

Near-Infrared-II Semiconducting Polymer Dots for Deep-tissue Fluorescence Imaging

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Keywords

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