@inproceedings{53382eecb80f4ad5bf593b10f8bb81a6,
title = "Multispectral fluorescence diffuse optical tomography",
abstract = "Fluorescence diffuse optical tomography (FDOT) has been widely used for in vivo small animal studies and the illposed problem in reconstruction can be eased by utilizing structural a priori obtained from an anatomic imaging modality. In this study, a multispectral fluorescence tomography (FT) is used, which has shown the ability to detect subtle shifts in the ICG absorption spectrum in our previous study. The imaging system is in trans-illumination mode with a swept-wavelength laser and a CCD on a rotation gantry and the structural image from the X-ray computed tomography is used to guide and constrain the FT reconstruction algorithm. In this work, a phantom with two inclusions filled with different fluorophores is utilized to evaluate whether the spectral information obtained using sweptwavelength laser can distinguish these two inclusions. The images are captured from 8 different views with three different wavelengths.",
keywords = "Diffuse Optical Tomography, Fluorescence Tomography, Frequency Domain, Multi-wavelength, NIR Swept Laser, Optical Imaging",
author = "Lo, {Pei An} and Jaedu Cho and Farouk Nouizi and Chiang, {Huihua Kenny} and Gultekin Gulsen",
note = "Publisher Copyright: {\textcopyright} 2017 SPIE.; null ; Conference date: 28-01-2017 Through 29-01-2017",
year = "2017",
doi = "10.1117/12.2251363",
language = "English",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Ramesh Raghavachari and Rongguang Liang",
booktitle = "Design and Quality for Biomedical Technologies X",
address = "United States",
}