Monte Carlo autofluorescence modeling on cervical dysplasia

Chih Er Wu; Shi How Hua; Shou Chia Chu; Chu Zhi Yu Chen; Jiu Chong Yuan; Huihua Kenny Chiang

doi:10.1109/APBP.2004.1412332

Monte Carlo autofluorescence modeling on cervical dysplasia

Chih Er Wu, Shi How Hua, Shou Chia Chu, Chu Zhi Yu Chen, Jiu Chong Yuan, Huihua Kenny Chiang^*

^*Corresponding author for this work

Department of Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

We present autofluorescence modeling of different cervix tissue dysplasia for clinical diagnosis. We used double integrating sphere system and inverse adding-doubling (IAD) method to evaluate tissue optical parameters (absorption coefficient, μ_a, scattering coefficient, μ_s) of different cervix dysplasia. We used fluorescence Monte Carlo model, included absorption coefficient and scattering coefficient from IAD and integrate sphere, to simulate autofluorescence spectra. The results show the increasing thickness of abnormal tissue on the cervical epithelium accompanied with the decreasing in autofluorescence intensity, in collagen peak (390 nm) and in NADH peak (460nm), along with the lesion developments.

Original language	English
Title of host publication	Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004
Pages	163-164
Number of pages	2
DOIs	https://doi.org/10.1109/APBP.2004.1412332
State	Published - Dec 2004
Event	Second Asian and Pacific Rim Symposium on Biophotonics, APBP 2004 - Taipei, Taiwan Duration: 15 Dec 2004 → 17 Dec 2004

Publication series

Name	Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004

Conference

Conference	Second Asian and Pacific Rim Symposium on Biophotonics, APBP 2004
Country/Territory	Taiwan
City	Taipei
Period	15/12/04 → 17/12/04

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10.1109/APBP.2004.1412332

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Wu, C. E., Hua, S. H., Chu, S. C., Chen, C. Z. Y., Yuan, J. C., & Chiang, H. K. (2004). Monte Carlo autofluorescence modeling on cervical dysplasia. In Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004 (pp. 163-164). (Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004). https://doi.org/10.1109/APBP.2004.1412332

@inproceedings{7b2f2c3959ee40a7b7e63a5fd7d4667f,

title = "Monte Carlo autofluorescence modeling on cervical dysplasia",

abstract = "We present autofluorescence modeling of different cervix tissue dysplasia for clinical diagnosis. We used double integrating sphere system and inverse adding-doubling (IAD) method to evaluate tissue optical parameters (absorption coefficient, μa, scattering coefficient, μs) of different cervix dysplasia. We used fluorescence Monte Carlo model, included absorption coefficient and scattering coefficient from IAD and integrate sphere, to simulate autofluorescence spectra. The results show the increasing thickness of abnormal tissue on the cervical epithelium accompanied with the decreasing in autofluorescence intensity, in collagen peak (390 nm) and in NADH peak (460nm), along with the lesion developments.",

author = "Wu, {Chih Er} and Hua, {Shi How} and Chu, {Shou Chia} and Chen, {Chu Zhi Yu} and Yuan, {Jiu Chong} and Chiang, {Huihua Kenny}",

year = "2004",

month = dec,

doi = "10.1109/APBP.2004.1412332",

language = "English",

isbn = "0780386760",

series = "Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004",

pages = "163--164",

booktitle = "Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004",

note = "Second Asian and Pacific Rim Symposium on Biophotonics, APBP 2004 ; Conference date: 15-12-2004 Through 17-12-2004",

}

Wu, CE, Hua, SH, Chu, SC, Chen, CZY, Yuan, JC & Chiang, HK 2004, Monte Carlo autofluorescence modeling on cervical dysplasia. in Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004. Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004, pp. 163-164, Second Asian and Pacific Rim Symposium on Biophotonics, APBP 2004, Taipei, Taiwan, 15/12/04. https://doi.org/10.1109/APBP.2004.1412332

Monte Carlo autofluorescence modeling on cervical dysplasia. / Wu, Chih Er; Hua, Shi How; Chu, Shou Chia et al.
Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004. 2004. p. 163-164 (Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Monte Carlo autofluorescence modeling on cervical dysplasia

AU - Wu, Chih Er

AU - Hua, Shi How

AU - Chu, Shou Chia

AU - Chen, Chu Zhi Yu

AU - Yuan, Jiu Chong

AU - Chiang, Huihua Kenny

PY - 2004/12

Y1 - 2004/12

N2 - We present autofluorescence modeling of different cervix tissue dysplasia for clinical diagnosis. We used double integrating sphere system and inverse adding-doubling (IAD) method to evaluate tissue optical parameters (absorption coefficient, μa, scattering coefficient, μs) of different cervix dysplasia. We used fluorescence Monte Carlo model, included absorption coefficient and scattering coefficient from IAD and integrate sphere, to simulate autofluorescence spectra. The results show the increasing thickness of abnormal tissue on the cervical epithelium accompanied with the decreasing in autofluorescence intensity, in collagen peak (390 nm) and in NADH peak (460nm), along with the lesion developments.

AB - We present autofluorescence modeling of different cervix tissue dysplasia for clinical diagnosis. We used double integrating sphere system and inverse adding-doubling (IAD) method to evaluate tissue optical parameters (absorption coefficient, μa, scattering coefficient, μs) of different cervix dysplasia. We used fluorescence Monte Carlo model, included absorption coefficient and scattering coefficient from IAD and integrate sphere, to simulate autofluorescence spectra. The results show the increasing thickness of abnormal tissue on the cervical epithelium accompanied with the decreasing in autofluorescence intensity, in collagen peak (390 nm) and in NADH peak (460nm), along with the lesion developments.

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U2 - 10.1109/APBP.2004.1412332

DO - 10.1109/APBP.2004.1412332

M3 - Conference contribution

AN - SCOPUS:20844455620

SN - 0780386760

T3 - Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004

SP - 163

EP - 164

BT - Second Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004

T2 - Second Asian and Pacific Rim Symposium on Biophotonics, APBP 2004

Y2 - 15 December 2004 through 17 December 2004

ER -

Monte Carlo autofluorescence modeling on cervical dysplasia

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