Monte Carlo autofluorescence modeling on cervical dysplasia

Chih Er Wu, Shi How Hua, Shou Chia Chu, Chu Zhi Yu Chen, Jiu Chong Yuan, Huihua Kenny Chiang*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We present autofluorescence modeling of different cervix tissue dysplasia for clinical diagnosis. We used double integrating sphere system and inverse adding-doubling (IAD) method to evaluate tissue optical parameters (absorption coefficient, μa, scattering coefficient, μs) of different cervix dysplasia. We used fluorescence Monte Carlo model, included absorption coefficient and scattering coefficient from IAD and integrate sphere, to simulate autofluorescence spectra. The results show the increasing thickness of abnormal tissue on the cervical epithelium accompanied with the decreasing in autofluorescence intensity, in collagen peak (390 nm) and in NADH peak (460nm), along with the lesion developments.

Original languageEnglish
Title of host publicationSecond Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004
Pages163-164
Number of pages2
DOIs
StatePublished - Dec 2004
EventSecond Asian and Pacific Rim Symposium on Biophotonics, APBP 2004 - Taipei, Taiwan
Duration: 15 Dec 200417 Dec 2004

Publication series

NameSecond Asian and Pacific Rim Symposium on Biophotonics - Proceedings, APBP 2004

Conference

ConferenceSecond Asian and Pacific Rim Symposium on Biophotonics, APBP 2004
Country/TerritoryTaiwan
CityTaipei
Period15/12/0417/12/04

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