TY - GEN
T1 - Monitoring of Vascular Response to Peri-Infarct Depolarization (PID) in Photothrombotic Stroke Animal Model
AU - Kao, Yu Chieh Jill
AU - Hsieh, Bao Yu
N1 - Publisher Copyright:
© 2019 IEEE.
PY - 2019/10
Y1 - 2019/10
N2 - Peri-infarct depolarization (PID) is abnormal transient depolarization waves slowly propagating in the cortex and confined in the ipsi-lesional cortex in accompanied with dramatic cerebral blood flow change. Ultrafast Doppler is a quantitative imaging method to investigate both CBF and CBV in a high spatiotemporal resolution and to measure the hemodynamic response of penetrating vessels in the cortex. In this study, the hemodynamics of cortical vessels during stroke-induced PID was monitored by the dynamic ultrafast Doppler under the animal model of photothrombotic stroke. The propagating PID-induced blood flow change (ΔCBV) initiated from the center of the stoke induction site and propagated outward in the right cortex. This study, for the first time, introduces a novel platform to demonstrate that dynamic ultrafast Doppler is feasible to monitor PID during acute stroke.
AB - Peri-infarct depolarization (PID) is abnormal transient depolarization waves slowly propagating in the cortex and confined in the ipsi-lesional cortex in accompanied with dramatic cerebral blood flow change. Ultrafast Doppler is a quantitative imaging method to investigate both CBF and CBV in a high spatiotemporal resolution and to measure the hemodynamic response of penetrating vessels in the cortex. In this study, the hemodynamics of cortical vessels during stroke-induced PID was monitored by the dynamic ultrafast Doppler under the animal model of photothrombotic stroke. The propagating PID-induced blood flow change (ΔCBV) initiated from the center of the stoke induction site and propagated outward in the right cortex. This study, for the first time, introduces a novel platform to demonstrate that dynamic ultrafast Doppler is feasible to monitor PID during acute stroke.
KW - functional ultrasound (fUS)
KW - peri-infarct depolarization (PID)
KW - stroke
KW - ultrafast Doppler
UR - http://www.scopus.com/inward/record.url?scp=85077576181&partnerID=8YFLogxK
U2 - 10.1109/ULTSYM.2019.8926239
DO - 10.1109/ULTSYM.2019.8926239
M3 - Conference contribution
AN - SCOPUS:85077576181
T3 - IEEE International Ultrasonics Symposium, IUS
SP - 235
EP - 238
BT - 2019 IEEE International Ultrasonics Symposium, IUS 2019
PB - IEEE Computer Society
T2 - 2019 IEEE International Ultrasonics Symposium, IUS 2019
Y2 - 6 October 2019 through 9 October 2019
ER -