Mechanism of repolarization change during initiation of supraventricular tachycardia

Yenn Jiang Lin, Ching Tai Tai, Chen En Chiang, Kun Tai Lee, Yoga Yuniadi, Bien Hsien Huang, Tu Ying Liu, Pi Chiang Lee, Jen Yuan Kuo, Shih Ann Chen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Repolarization Changes During SVT. Introduction: Previous literature has documented the association between narrow QRS supraventricular tachycardia (SVT) and pronounced ST-T segment change. The aim of this study was to evaluate repolarization changes during SVT initiation and demonstrate the possible mechanism. Methods and Results: Fifty-one consecutive patients (20 men and 31 women; mean age 46.1 ± 16.4 years) with narrow QRS SVT (32 patients with AV nodal reentrant tachycardia and 19 patients with AV reentrant tachycardia) were included. We retrospectively analyzed the intracardiac recordings and ST-T segment changes on 12-lead surface ECGs during SVT initiation. Twenty-six (51%) patients developed ST segment repolarization changes during SVT initiation. Patients with shorter baseline sinus cycle length, shorter tachycardia cycle length, elevated systolic blood pressure before tachycardia induction, and greater reduction of systolic blood pressure had a higher incidence of repolarization changes. However, multivariate analysis showed that reduction of systolic blood pressure after SVT induction was the only independent predictor of repolarization changes. Furthermore, the maximal degree of ST segment depression during SVT correlated with the reduction of systolic blood pressure (r = 0.75, P < 0.001). Conclusion: Repolarization changes during SVT initiation were caused mainly by concurrent hemodynamic change after SVT initiation with abrupt cycle length shortening.

Original languageEnglish
Pages (from-to)1233-1237
Number of pages5
JournalJournal of cardiovascular electrophysiology
Issue number11
StatePublished - Nov 2004


  • Blood pressure
  • Repolarization
  • Supraventricular tachycardia


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