Measurement of central systolic blood pressure by pulse volume plethysmography with a noninvasive blood pressure monitor

Shih Hsien Sung, Hao Min Cheng, Shao Yuan Chuang, Yuan Ta Shih, Kang Ling Wang, Ying Hwa Chen, Shing Jong Lin, Wen Chung Yu, Chen Huan Chen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Background Central systolic blood pressure (SBP) can be estimated by an oscillometric method developed from a pulse volume plethysmography (PVP) device. The present study applied this novel method to a noninvasive blood pressure monitor (NBPM). Methods We enrolled 50 patients (37 men, age range 30-84 years) referred for cardiac catheterization. Invasive right brachial and central aortic pressures (using a dual-sensor pressure catheter), and noninvasive left brachial SBP and diastolic blood pressure (DBP), and PVP waveform (using a customized NBPM) were simultaneously recorded. Central SBP was estimated by analysis of the PVP waveform calibrated to the noninvasive SBP and DBP, using both the original (CSBP-O) and the newly generated (CSBP-N) regression equations. The reproducibility of the invasive central SBP by CSBP-O and CSBP-N was examined using the concordance correlation coefficient. Results Overall, the invasive central aortic SBP ranged 86-176 with a mean of 124 21 mm Hg. The mean differences between the estimated and the invasive central SBP were 1.3 ± 6.7 mm Hg for CSBP-O and 0.0 ± 6.2 mm Hg for CSBP-N, respectively. The concordance correlation coefficients for CSBP-O and CSBP-N were 0.94 (95% confidence interval (CI): 0.93-0.94) and 0.95 (95% CI: 0.95-0.96), and both were significantly better than that for the noninvasive brachial SBP (0.87, 0.84-0.91) indicated by non-overlapping CIs.ConclusionsThe PVP method for noninvasive estimation of central SBP can be applied to a commonly used NBPM. Whether the NBPM-derived central SBP is superior to the noninvasive brachial SBP in the prediction of cardiovascular risks remains to be investigated.

Original languageEnglish
Pages (from-to)542-548
Number of pages7
JournalAmerican Journal of Hypertension
Issue number5
StatePublished - May 2012


  • blood pressure
  • central blood pressure
  • hypertension
  • noninvasive method
  • oscillometry
  • pulse volume plethysmography


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