Lymphatic vessel segmentation in optical coherence tomography by adding U-Net-based CNN for artifact minimization

Pei Yu Lai, Chung Hsing Chang, Hong Ren Su, Wen Chuan Kuo*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The lymphatic system branches throughout the body to transport bodily fluid and plays a key immune-response role. Optical coherence tomography (OCT) is an emerging technique for the noninvasive and label-free imaging of lymphatic capillaries utilizing low scattering features of the lymph fluid. Here, the proposed lymphatic segmentation method combines U-Net-based CNN, a Hessian vesselness filter, and a modified intensity-thresholding to search the nearby pixels based on the binarized Hessian mask. Compared to previous approaches, the method can extract shapes more precisely, and the segmented result contains minimal artifacts, achieves the dice coefficient of 0.83, precision of 0.859, and recall of 0.803.

Original languageEnglish
Pages (from-to)2679-2693
Number of pages15
JournalBiomedical Optics Express
Volume11
Issue number5
DOIs
StatePublished - 1 May 2020

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