Liquid crystal-based capacitive, electro-optical and dielectric biosensors for protein quantitation

Mon Juan Lee*, Wei Lee

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

The electrical, electro-optical and dielectric properties of liquid crystals (LCs) are routinely manipulated in liquid-crystal display (LCD) devices, but their potential application in the development of biosensors is still in a nascent stage. In this review, utilising the electrical properties, electro-optical effect and dielectric anisotropy in LCs, we provide insights into several possible modes of label-free biodetection and describe how capacitance, electro-optical and dielectric measurements of various LCs assist in quantitative analysis of biomolecules. It is concluded that the electrically induced biosensing techniques proposed here provides new incentives for researchers to study the interaction between LCs and biomolecules and to resolve technical hurdles facing the development of LC-based biosensors.

Original languageEnglish
Pages (from-to)1145-1153
Number of pages9
JournalLiquid Crystals
Volume47
Issue number8
DOIs
StatePublished - 20 Jun 2020
Event4th Asian Conference on Liquid Crystals (ACLC) - Shenzhen, China
Duration: 17 Jan 201918 Jan 2019

Keywords

  • biosensing
  • bovine serum albumin
  • capacitance
  • dielectric spectroscopy
  • Electro-optical measurement
  • protein

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