Liquid-crystal-based biosensing beyond texture observations

Mon Juan Lee*, Chi Hao Lin, Wei Lee

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

14 Scopus citations

Abstract

The texture observation has long been the core technique in liquid crystal (LC)-based biosensing. One of the drawbacks of this observational means is the difficulty in quantitative analysis. In this invited paper, we report on our recent attempt to improve the LC-based biosensing technique through the analysis of bovine serum albumin (BSA), a protein standard commonly used in the assay of protein concentration. We propose to overcome the technical limitations in the analysis of LC-based biosensors by considering alternative measuring schemes. By means of the induced changes in electro-optical properties of LCs in the presence of different concentrations of BSA, novel quantitative techniques specific for LC-based biosensors are developed.

Original languageEnglish
Title of host publicationLiquid Crystals XIX
EditorsIam Choon Khoo
PublisherSPIE
ISBN (Electronic)9781628417319
DOIs
StatePublished - 1 Jan 2015
EventLiquid Crystals XIX - San Diego, United States
Duration: 9 Aug 201510 Aug 2015

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume9565
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceLiquid Crystals XIX
Country/TerritoryUnited States
CitySan Diego
Period9/08/1510/08/15

Keywords

  • Biophotonics
  • Biosensors
  • Bovine serum albumin
  • Electro-optical properties
  • Liquid crystals
  • Protein

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