Abstract
label-free and array-based optical liquid-crystal (LC) immunodetection technique for the detection of CA125 antigen, a protein biomarker most frequently used for ovarian cancer detection, was demonstrated with a nematic LC with larger birefringence (Än) to promote sensitivity in detecting biomolecules. The LC-based immunodetection offers an alternative and sensitive approach for the detection of biomarker proteins, with the potential of replacing conventional immunoassays used in biochemical studies and clinical laboratories
Original language | English |
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Article number | 077006 |
Journal | Journal of Biomedical Optics |
Volume | 19 |
Issue number | 7 |
DOIs | |
State | Published - 1 Jan 2014 |
Keywords
- CA125
- cancer biomarker
- label-free immunodetection
- liquid-crystal-based immunodetection