ISPMER: Integrated system for combined PET, MRI, and electrophysiological recording in somatosensory studies in rats

Yen Yu Shih, You Yin Chen, Jyh Cheng Chen, Chen Chang, Fu Shan Jaw*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

The present study developed an integrated system for use in combined PET, MRI, and electrophysiological recording in somatosensory studies in rats, called ISPMER. A stereotaxic frame was designed for animal positioning that could be used in all three measurement modalities, and its dimensions complied with the gold standard of the Paxinos and Watson rat brain atlas. A graphical user interface was developed for analyzing the data using several signal processing algorithms. This integrated system provides a novel interface for the recording and processing of three-dimensional neuronal signals in three modalities.

Original languageEnglish
Pages (from-to)938-943
Number of pages6
JournalNuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume580
Issue number2
DOIs
StatePublished - 1 Oct 2007

Keywords

  • Electrophysiology
  • MRI
  • PET
  • Rat
  • Stereotaxic frame

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