Intra-Arterial Thrombolytic Therapy Is Not a Therapeutic Option for Filler-Related Central Retinal Artery Occlusion

Yi Chun Chen, Hsiu Mei Wu, Shih Jen Chen, Han Jui Lee, Jiing Feng Lirng, Chung Jung Lin, Feng Chi Chang*, Chao Bao Luo, Wan Yuo Guo

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Cosmetic facial filler-related central retinal artery occlusion (CRAO) is a devastating complication of facial hyaluronic acid (HA) injection and can be managed by intra-arterial thrombolytic therapy (IATT). The authors report on a 20-year-old woman who developed unilateral CRAO due to facial HA injection and who, despite prompt IATT, lost vision. A review of the related literature found 14 other female patients who developed cosmetic facial filler-related CRAO and accepted IATT management. In no case was vision loss clinically improved. IATT is not an effective preventive treatment of dermal filler-associated CRAO. The authors suggest careful preprocedural patient selection to prevent this complication.

Original languageEnglish
Pages (from-to)325-329
Number of pages5
JournalFacial Plastic Surgery
Volume34
Issue number3
DOIs
StatePublished - 1 Jun 2018

Keywords

  • central retinal artery occlusion
  • dermal filler
  • hyaluronic acid
  • hyaluronidase
  • intra-arterial thrombolytic therapy

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