Influence of Dialysis Membranes on Clinical Outcomes: From History to Innovation

Yee An Chen, Shuo Ming Ou*, Chih Ching Lin

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Dialysis membranes were traditionally classified according to their material compositions (i.e., as cellulosic or synthetic) and on the basis of the new concept of the sieving coefficient (deter-mined by the molecular weight retention onset and molecular weight cut-off). The advantages of synthetic polymer membranes over cellulose membranes are also described on the basis of their physical, chemical, and structural properties. Innovations of dialysis membrane in recent years include the development of medium cutoff membranes; graphene oxide membranes; mixed-matrix membranes; bioartificial kidneys; and membranes modified with vitamin E, lipoic acid, and neutrophil elastase inhibitors. The current state of research on these membranes, their effects on clinical outcomes, the advantages and disadvantages of their use, and their potential for clinical use are outlined and described.

Original languageEnglish
Article number152
Issue number2
StatePublished - Feb 2022


  • Cellulose membranes
  • Dialysis membranes
  • Graphene oxide membranes
  • Mixed-matrix membranes
  • Synthetic polymer membranes


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