Imaging pulsatile retinal blood flow in human eye

Bin Rao*, Lingfeng Yu, Huihua Kenny Chiang, Leandro C. Zacharias, Ronald M. Kurtz, Baruch D. Kuppermann, Zhongping Chen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


A functional Fourier domain optical coherence tomography instrument offering spectral Doppler imaging of in vivo pulsatile human retinal blood flow was constructed. An improved phase-resolved algorithm was developed to correct bulk motion artifacts. Spectral Doppler imaging provides complementary temporal flow information to the spatially distributed flow information of the color Doppler image by providing direct visualization of the Doppler spectrum of the flow whose pattern can be further quantified with various velocity envelope curves and their corresponding flow indices. The coefficient of repeatability on resistance index measurement was assessed by analyzing 14 measurements on two vessels within two normal subjects.

Original languageEnglish
Article number040505
JournalJournal of Biomedical Optics
Issue number4
StatePublished - 2008


  • doppler
  • interferometry
  • tomography


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