How the severity and mechanism of recurrent laryngeal nerve dysfunction during monitored thyroidectomy impact on postoperative voice

Tzu Yen Huang; Wing Hei Viola Yu; Feng Yu Chiang; Che Wei Wu; Shih Chen Fu; An Shun Tai; Yi Chu Lin; Hsin Yi Tseng; Ka Wo Lee; Sheng Hsuan Lin

doi:10.3390/cancers13215379

How the severity and mechanism of recurrent laryngeal nerve dysfunction during monitored thyroidectomy impact on postoperative voice

Tzu Yen Huang, Wing Hei Viola Yu, Feng Yu Chiang, Che Wei Wu, Shih Chen Fu, An Shun Tai, Yi Chu Lin, Hsin Yi Tseng, Ka Wo Lee, Sheng Hsuan Lin^*

^*Corresponding author for this work

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12 Scopus citations

Abstract

Intraoperative neuromonitoring can qualify and quantify RLN function during thyroid surgery. This study investigated how the severity and mechanism of RLN dysfunction during monitored thyroid surgery affected postoperative voice. This retrospective study analyzed 1021 patients that received standardized monitored thyroidectomy. Patients had post-dissection RLN(R2) signal <50%, 50–90% and >90% decrease from pre-dissection RLN(R1) signal were classified into Group A-no/mild, B-moderate, and C-severe RLN dysfunction, respectively. Demographic characteristics, RLN injury mechanisms(mechanical/thermal) and voice analysis parameters were recorded. More patients in the group with higher severity of RLN dysfunction had malignant pathology results (A/B/C = 35%/48%/55%, p = 0.017), received neck dissection (A/B/C = 17%/31%/55%, p < 0.001), had.

Original language	English
Article number	5379
Journal	Cancers
Volume	13
Issue number	21
DOIs	https://doi.org/10.3390/cancers13215379
State	Published - 1 Nov 2021

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@article{ef2484fd85a04347b1009099ea2c1f08,

title = "How the severity and mechanism of recurrent laryngeal nerve dysfunction during monitored thyroidectomy impact on postoperative voice",

abstract = "Intraoperative neuromonitoring can qualify and quantify RLN function during thyroid surgery. This study investigated how the severity and mechanism of RLN dysfunction during monitored thyroid surgery affected postoperative voice. This retrospective study analyzed 1021 patients that received standardized monitored thyroidectomy. Patients had post-dissection RLN(R2) signal <50%, 50–90% and >90% decrease from pre-dissection RLN(R1) signal were classified into Group A-no/mild, B-moderate, and C-severe RLN dysfunction, respectively. Demographic characteristics, RLN injury mechanisms(mechanical/thermal) and voice analysis parameters were recorded. More patients in the group with higher severity of RLN dysfunction had malignant pathology results (A/B/C = 35%/48%/55%, p = 0.017), received neck dissection (A/B/C = 17%/31%/55%, p < 0.001), had.",

author = "Huang, {Tzu Yen} and Yu, {Wing Hei Viola} and Chiang, {Feng Yu} and Wu, {Che Wei} and Fu, {Shih Chen} and Tai, {An Shun} and Lin, {Yi Chu} and Tseng, {Hsin Yi} and Lee, {Ka Wo} and Lin, {Sheng Hsuan}",

note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2021",

month = nov,

day = "1",

doi = "10.3390/cancers13215379",

language = "English",

volume = "13",

journal = "Cancers",

issn = "2072-6694",

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AU - Huang, Tzu Yen

AU - Yu, Wing Hei Viola

AU - Chiang, Feng Yu

AU - Wu, Che Wei

AU - Fu, Shih Chen

AU - Tai, An Shun

AU - Lin, Yi Chu

AU - Tseng, Hsin Yi

AU - Lee, Ka Wo

AU - Lin, Sheng Hsuan

PY - 2021/11/1

Y1 - 2021/11/1

N2 - Intraoperative neuromonitoring can qualify and quantify RLN function during thyroid surgery. This study investigated how the severity and mechanism of RLN dysfunction during monitored thyroid surgery affected postoperative voice. This retrospective study analyzed 1021 patients that received standardized monitored thyroidectomy. Patients had post-dissection RLN(R2) signal <50%, 50–90% and >90% decrease from pre-dissection RLN(R1) signal were classified into Group A-no/mild, B-moderate, and C-severe RLN dysfunction, respectively. Demographic characteristics, RLN injury mechanisms(mechanical/thermal) and voice analysis parameters were recorded. More patients in the group with higher severity of RLN dysfunction had malignant pathology results (A/B/C = 35%/48%/55%, p = 0.017), received neck dissection (A/B/C = 17%/31%/55%, p < 0.001), had.

AB - Intraoperative neuromonitoring can qualify and quantify RLN function during thyroid surgery. This study investigated how the severity and mechanism of RLN dysfunction during monitored thyroid surgery affected postoperative voice. This retrospective study analyzed 1021 patients that received standardized monitored thyroidectomy. Patients had post-dissection RLN(R2) signal <50%, 50–90% and >90% decrease from pre-dissection RLN(R1) signal were classified into Group A-no/mild, B-moderate, and C-severe RLN dysfunction, respectively. Demographic characteristics, RLN injury mechanisms(mechanical/thermal) and voice analysis parameters were recorded. More patients in the group with higher severity of RLN dysfunction had malignant pathology results (A/B/C = 35%/48%/55%, p = 0.017), received neck dissection (A/B/C = 17%/31%/55%, p < 0.001), had.

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U2 - 10.3390/cancers13215379

DO - 10.3390/cancers13215379

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VL - 13

JO - Cancers

JF - Cancers

IS - 21

M1 - 5379

ER -

How the severity and mechanism of recurrent laryngeal nerve dysfunction during monitored thyroidectomy impact on postoperative voice

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