How can chip technology realize electronic sensing of viruses?

Hiroshi Watanabe, Che An Lee*

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

    Abstract

    Regrettably, COVID-19 taught us how significant the portable virus sensing technology is. Before it, the cost issues and different regulations in various countries have hindered the widespread use of the Point-of-Care Testing (POCT). Suppose we can electronically control it using Si nanotechnology, named e-POCT. Following the concept of IoT sensors, we can expect that a plenty of deployed e- POCTs may retrieve digital data about where, when, how much, and which virus is being spread. The collected digital data (to be BigData) can be analyzed by AI machines to optimize the global distribution of medical resources. The core technology for e-POCT must be an electronic biosensing. It is composed of a controlling system to selectively collect biomolecules (specific to targeted virus) in specimen solutions, oxide films (or membranes, polymers) to adhere specific biomolecules, and a sensing system to convert the adhered biomolecules to electrical signals. The efficiencies and reliabilities of the components are critical to the performance of the virus sensing. The performance can be characterized by the Limit-of-Detection (LoD) and detection time. We propose a concept of electronic sensing systems to substantially improve both LoD and detection time.

    Original languageEnglish
    Title of host publicationVLSI-TSA 2021 - 2021 International Symposium on VLSI Technology, Systems and Applications, Proceedings
    PublisherInstitute of Electrical and Electronics Engineers Inc.
    ISBN (Electronic)9781665419345
    DOIs
    StatePublished - 19 Apr 2021
    Event2021 International Symposium on VLSI Technology, Systems and Applications, VLSI-TSA 2021 - Hsinchu, Taiwan
    Duration: 19 Apr 202122 Apr 2021

    Publication series

    NameVLSI-TSA 2021 - 2021 International Symposium on VLSI Technology, Systems and Applications, Proceedings

    Conference

    Conference2021 International Symposium on VLSI Technology, Systems and Applications, VLSI-TSA 2021
    Country/TerritoryTaiwan
    CityHsinchu
    Period19/04/2122/04/21

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