Guillain-Barré syndrome in a heart transplantation recipient

Ching Wen Wei, Chin Yu Liu, Chung Yi Chang, Wei Chun Liu, Hao Chun Cheng, Heng Hsin Tung, Nian Chen Chiang, Hsin Huei Chang

Research output: Contribution to journalArticlepeer-review


ABSTRACT: A rare case of a heart transplantation recipient with Guillain-Barré syndrome occurred, which was associated with peripheral nervous system damage. Based on a review of epidemiological research, the symptom development process, and diagnostic tools, the authors highlight the extreme rarity of this postinfectious immune disease. After diagnosis, plasma exchange and immunoregulatory therapy should be performed because they result in rapid recovery. If there is delayed diagnosis and treatment, there is a high risk of disability or death. When patients experience acute limb paralysis as the main symptom, nurse practitioners (NPs) should focus on the patient's history, particularly with regard to infectious agents. Closely monitoring the patient to detect respiratory failure and the need for early respiratory intervention can help the patient to avoid the severe complication of permanent brain injury. For NPs, performance of early differential diagnosis is important, especially among patients who have immunosuppressive dependence after transplantation.

Original languageEnglish
Pages (from-to)639-645
Number of pages7
JournalJournal of the American Association of Nurse Practitioners
Issue number8
StatePublished - 8 Apr 2020


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