Graphene oxide dot-based microstructures via dispersion and support of bovine serum albumin

Hsin Yu Chang; Chun Yu Lin; Chia Yuan Chang; Hsisheng Teng; Paul J. Campagnola; Shean Jen Chen

doi:10.1364/OME.6.003193

Graphene oxide dot-based microstructures via dispersion and support of bovine serum albumin

Hsin Yu Chang, Chun Yu Lin, Chia Yuan Chang, Hsisheng Teng, Paul J. Campagnola, Shean Jen Chen^*

^*Corresponding author for this work

Institute of Imaging and Biomedical Photonics

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Three-dimensional graphene oxide-based microstructures have great potential for use in microelectronic and biomedical applications and can be fabricated by using two-photon excitation photochemical processes. In such excitation processes, rose Bengal is the preferred candidate as the photoactivator in two-photon crosslinking; nevertheless, it induces graphene oxide self-aggregation. Herein, bovine serum albumin (BSA) is adopted to prevent graphene oxide dot (GOD) aggregation even at very high GOD fabrication-solution concentrations, yet still supports GOD microstructures. In this manner, three-dimensional freeform GOD microstructures with different GOD concentrations were developed. Furthermore, the biocomparability of the GOD microstructure with the help of added biomaterials such as BSA was verified under living cell incubation.

Original language	English
Pages (from-to)	3193-3201
Number of pages	9
Journal	Optical Materials Express
Volume	6
Issue number	10
DOIs	https://doi.org/10.1364/OME.6.003193
State	Published - 2016

Access to Document

10.1364/OME.6.003193

Cite this

@article{ea62778e5c7a481a8429125291057899,

title = "Graphene oxide dot-based microstructures via dispersion and support of bovine serum albumin",

abstract = "Three-dimensional graphene oxide-based microstructures have great potential for use in microelectronic and biomedical applications and can be fabricated by using two-photon excitation photochemical processes. In such excitation processes, rose Bengal is the preferred candidate as the photoactivator in two-photon crosslinking; nevertheless, it induces graphene oxide self-aggregation. Herein, bovine serum albumin (BSA) is adopted to prevent graphene oxide dot (GOD) aggregation even at very high GOD fabrication-solution concentrations, yet still supports GOD microstructures. In this manner, three-dimensional freeform GOD microstructures with different GOD concentrations were developed. Furthermore, the biocomparability of the GOD microstructure with the help of added biomaterials such as BSA was verified under living cell incubation.",

author = "Chang, {Hsin Yu} and Lin, {Chun Yu} and Chang, {Chia Yuan} and Hsisheng Teng and Campagnola, {Paul J.} and Chen, {Shean Jen}",

note = "Publisher Copyright: {\textcopyright} 2016 Optical Society of America.",

year = "2016",

doi = "10.1364/OME.6.003193",

language = "English",

volume = "6",

pages = "3193--3201",

journal = "Optical Materials Express",

issn = "2159-3930",

publisher = "Optica Publishing Group (formerly OSA)",

number = "10",

}

TY - JOUR

T1 - Graphene oxide dot-based microstructures via dispersion and support of bovine serum albumin

AU - Chang, Hsin Yu

AU - Lin, Chun Yu

AU - Chang, Chia Yuan

AU - Teng, Hsisheng

AU - Campagnola, Paul J.

AU - Chen, Shean Jen

PY - 2016

Y1 - 2016

N2 - Three-dimensional graphene oxide-based microstructures have great potential for use in microelectronic and biomedical applications and can be fabricated by using two-photon excitation photochemical processes. In such excitation processes, rose Bengal is the preferred candidate as the photoactivator in two-photon crosslinking; nevertheless, it induces graphene oxide self-aggregation. Herein, bovine serum albumin (BSA) is adopted to prevent graphene oxide dot (GOD) aggregation even at very high GOD fabrication-solution concentrations, yet still supports GOD microstructures. In this manner, three-dimensional freeform GOD microstructures with different GOD concentrations were developed. Furthermore, the biocomparability of the GOD microstructure with the help of added biomaterials such as BSA was verified under living cell incubation.

AB - Three-dimensional graphene oxide-based microstructures have great potential for use in microelectronic and biomedical applications and can be fabricated by using two-photon excitation photochemical processes. In such excitation processes, rose Bengal is the preferred candidate as the photoactivator in two-photon crosslinking; nevertheless, it induces graphene oxide self-aggregation. Herein, bovine serum albumin (BSA) is adopted to prevent graphene oxide dot (GOD) aggregation even at very high GOD fabrication-solution concentrations, yet still supports GOD microstructures. In this manner, three-dimensional freeform GOD microstructures with different GOD concentrations were developed. Furthermore, the biocomparability of the GOD microstructure with the help of added biomaterials such as BSA was verified under living cell incubation.

UR - http://www.scopus.com/inward/record.url?scp=84992073878&partnerID=8YFLogxK

U2 - 10.1364/OME.6.003193

DO - 10.1364/OME.6.003193

M3 - Article

AN - SCOPUS:84992073878

SN - 2159-3930

VL - 6

SP - 3193

EP - 3201

JO - Optical Materials Express

JF - Optical Materials Express

IS - 10

ER -

Graphene oxide dot-based microstructures via dispersion and support of bovine serum albumin

Abstract

Access to Document

Other files and links

Fingerprint

Cite this