Gold Nanoparticles as a Biosensor for Cancer Biomarker Determination

Chien Hsiu Li, Ming Hsien Chan, Yu Chan Chang, Michael Hsiao*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


Molecular biology applications based on gold nanotechnology have revolutionary impacts, especially in diagnosing and treating molecular and cellular levels. The combination of plasmonic resonance, biochemistry, and optoelectronic engineering has increased the detection of molecules and the possibility of atoms. These advantages have brought medical research to the cellular level for application potential. Many research groups are working towards this. The superior analytical properties of gold nanoparticles can not only be used as an effective drug screening instrument for gene sequencing in new drug development but also as an essential tool for detecting physiological functions, such as blood glucose, antigen-antibody analysis, etc. The review introduces the principles of biomedical sensing systems, the principles of nanomaterial analysis applied to biomedicine at home and abroad, and the chemical surface modification of various gold nanoparticles.

Original languageEnglish
Article number364
Issue number1
StatePublished - Jan 2023


  • biosensing
  • cancer marker
  • gold nanoparticles
  • surface modification
  • surface plasmon resonance


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