Feasibility study of optimizing PET/CT acquisition protocol between image quality and radiation dose

T. H. Wu; T. C. Chu; Y. H. Huang; C. L. Chen; S. Y. Wang; J. S. Lee

doi:10.1109/NSSMIC.2003.1352381

Feasibility study of optimizing PET/CT acquisition protocol between image quality and radiation dose

T. H. Wu, T. C. Chu, Y. H. Huang, C. L. Chen, S. Y. Wang, J. S. Lee^*

^*Corresponding author for this work

Department of Biomedical Imaging and Radiological Sciences

Research output: Contribution to journal › Conference article › peer-review

Abstract

In current combined PET/CT systems, high-quality CT images not only increase the diagnostic values by providing anatomic delineation of hyper- and hypo-metabolic tissues but also offer shorter transmission scanning times compared to standard PET imaging. However, this approach potentially introduces radiation burden due to the higher radiation exposure. Ideally operation protocols for routine PET/CT imaging take diagnostic values, image quality, clinical practicability, scanning time and radiation doses into consideration, but the question of how to reconcile all these factors is made debated topic in nuclear medicine today. In this study, the radiation doses delivered from a typical germanium-based and CT-based transmission scan were measured by means of an anthropomorphic Rando Alderson phantom with insertion of thermoluminescent dosimeters and the image effects of the attenuation correction with various CT acquisition protocols were compared. From the results, we found that image properties and attenuation correction data did not differ significantly by adjusted CT acquisition parameters in PET/CT imaging for reduced patient exposure about 1/26 compared to the currently used while maintaining the advantages of short scanning time and clinical practicability.

Original language	English
Article number	M7-126
Pages (from-to)	2410-2414
Number of pages	5
Journal	IEEE Nuclear Science Symposium Conference Record
Volume	4
DOIs	https://doi.org/10.1109/NSSMIC.2003.1352381
State	Published - Oct 2003
Event	2003 IEEE Nuclear Science Symposium Conference Record - Nuclear Science Symposium, Medical Imaging Conference - Portland, OR, United States Duration: 19 Oct 2003 → 25 Oct 2003

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title = "Feasibility study of optimizing PET/CT acquisition protocol between image quality and radiation dose",

abstract = "In current combined PET/CT systems, high-quality CT images not only increase the diagnostic values by providing anatomic delineation of hyper- and hypo-metabolic tissues but also offer shorter transmission scanning times compared to standard PET imaging. However, this approach potentially introduces radiation burden due to the higher radiation exposure. Ideally operation protocols for routine PET/CT imaging take diagnostic values, image quality, clinical practicability, scanning time and radiation doses into consideration, but the question of how to reconcile all these factors is made debated topic in nuclear medicine today. In this study, the radiation doses delivered from a typical germanium-based and CT-based transmission scan were measured by means of an anthropomorphic Rando Alderson phantom with insertion of thermoluminescent dosimeters and the image effects of the attenuation correction with various CT acquisition protocols were compared. From the results, we found that image properties and attenuation correction data did not differ significantly by adjusted CT acquisition parameters in PET/CT imaging for reduced patient exposure about 1/26 compared to the currently used while maintaining the advantages of short scanning time and clinical practicability.",

author = "Wu, {T. H.} and Chu, {T. C.} and Huang, {Y. H.} and Chen, {C. L.} and Wang, {S. Y.} and Lee, {J. S.}",

year = "2003",

month = oct,

doi = "10.1109/NSSMIC.2003.1352381",

language = "English",

volume = "4",

pages = "2410--2414",

journal = "IEEE Nuclear Science Symposium Conference Record",

issn = "1095-7863",

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note = "2003 IEEE Nuclear Science Symposium Conference Record - Nuclear Science Symposium, Medical Imaging Conference ; Conference date: 19-10-2003 Through 25-10-2003",

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AU - Wu, T. H.

AU - Chu, T. C.

AU - Huang, Y. H.

AU - Chen, C. L.

AU - Wang, S. Y.

AU - Lee, J. S.

PY - 2003/10

Y1 - 2003/10

N2 - In current combined PET/CT systems, high-quality CT images not only increase the diagnostic values by providing anatomic delineation of hyper- and hypo-metabolic tissues but also offer shorter transmission scanning times compared to standard PET imaging. However, this approach potentially introduces radiation burden due to the higher radiation exposure. Ideally operation protocols for routine PET/CT imaging take diagnostic values, image quality, clinical practicability, scanning time and radiation doses into consideration, but the question of how to reconcile all these factors is made debated topic in nuclear medicine today. In this study, the radiation doses delivered from a typical germanium-based and CT-based transmission scan were measured by means of an anthropomorphic Rando Alderson phantom with insertion of thermoluminescent dosimeters and the image effects of the attenuation correction with various CT acquisition protocols were compared. From the results, we found that image properties and attenuation correction data did not differ significantly by adjusted CT acquisition parameters in PET/CT imaging for reduced patient exposure about 1/26 compared to the currently used while maintaining the advantages of short scanning time and clinical practicability.

AB - In current combined PET/CT systems, high-quality CT images not only increase the diagnostic values by providing anatomic delineation of hyper- and hypo-metabolic tissues but also offer shorter transmission scanning times compared to standard PET imaging. However, this approach potentially introduces radiation burden due to the higher radiation exposure. Ideally operation protocols for routine PET/CT imaging take diagnostic values, image quality, clinical practicability, scanning time and radiation doses into consideration, but the question of how to reconcile all these factors is made debated topic in nuclear medicine today. In this study, the radiation doses delivered from a typical germanium-based and CT-based transmission scan were measured by means of an anthropomorphic Rando Alderson phantom with insertion of thermoluminescent dosimeters and the image effects of the attenuation correction with various CT acquisition protocols were compared. From the results, we found that image properties and attenuation correction data did not differ significantly by adjusted CT acquisition parameters in PET/CT imaging for reduced patient exposure about 1/26 compared to the currently used while maintaining the advantages of short scanning time and clinical practicability.

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AN - SCOPUS:11844269263

SN - 1095-7863

VL - 4

SP - 2410

EP - 2414

JO - IEEE Nuclear Science Symposium Conference Record

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T2 - 2003 IEEE Nuclear Science Symposium Conference Record - Nuclear Science Symposium, Medical Imaging Conference

Y2 - 19 October 2003 through 25 October 2003

ER -

Feasibility study of optimizing PET/CT acquisition protocol between image quality and radiation dose

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