Fabrication and functionalization of three-dimensional well-defined scaffolds using novel carbon dioxide assisted microfabrication

Yong Yang, Shubhayu Basu, L. James Lee, Shang Tian Yang

Research output: Contribution to conferencePaperpeer-review

Abstract

The construction of 3D scaffolds with well-defined microstructure using a biologically benign carbon dioxide assisted microfabrication (CAMF) was discussed. Astrocytes were cultured in three dimensions in the poly(DL-lactide-co-glycolide) (PLGA) scaffolds and in two dimensions on PLGA films comparison. Low pressure CO 2 was introduced to increase the free volume among the polymer chains. The results show that the scaffold can support cell densities as high as 2.8×10 7 - 5.0×10 7 cells/ml of the scaffold volume.

Original languageEnglish
Pages1301-1303
Number of pages3
StatePublished - Nov 2004
Event2004 AIChE Annual Meeting - Austin, TX, United States
Duration: 7 Nov 200412 Nov 2004

Conference

Conference2004 AIChE Annual Meeting
Country/TerritoryUnited States
CityAustin, TX
Period7/11/0412/11/04

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