Fabrication and functionalization of three-dimensional well-defined scaffolds using novel carbon dioxide assisted microfabrication

Yong Yang; Shubhayu Basu; L. James Lee; Shang Tian Yang

Fabrication and functionalization of three-dimensional well-defined scaffolds using novel carbon dioxide assisted microfabrication

Yong Yang, Shubhayu Basu, L. James Lee, Shang Tian Yang

Institute of Biopharmaceutical Sciences

Research output: Contribution to conference › Paper › peer-review

Abstract

The construction of 3D scaffolds with well-defined microstructure using a biologically benign carbon dioxide assisted microfabrication (CAMF) was discussed. Astrocytes were cultured in three dimensions in the poly(DL-lactide-co-glycolide) (PLGA) scaffolds and in two dimensions on PLGA films comparison. Low pressure CO ₂ was introduced to increase the free volume among the polymer chains. The results show that the scaffold can support cell densities as high as 2.8×10 ⁷ - 5.0×10 ⁷ cells/ml of the scaffold volume.

Original language	English
Pages	1301-1303
Number of pages	3
State	Published - Nov 2004
Event	2004 AIChE Annual Meeting - Austin, TX, United States Duration: 7 Nov 2004 → 12 Nov 2004

Conference

Conference	2004 AIChE Annual Meeting
Country/Territory	United States
City	Austin, TX
Period	7/11/04 → 12/11/04

Cite this

@conference{b212f2482c504be6b4d3abbb7b30250d,

title = "Fabrication and functionalization of three-dimensional well-defined scaffolds using novel carbon dioxide assisted microfabrication",

abstract = "The construction of 3D scaffolds with well-defined microstructure using a biologically benign carbon dioxide assisted microfabrication (CAMF) was discussed. Astrocytes were cultured in three dimensions in the poly(DL-lactide-co-glycolide) (PLGA) scaffolds and in two dimensions on PLGA films comparison. Low pressure CO 2 was introduced to increase the free volume among the polymer chains. The results show that the scaffold can support cell densities as high as 2.8×10 7 - 5.0×10 7 cells/ml of the scaffold volume.",

author = "Yong Yang and Shubhayu Basu and Lee, {L. James} and Yang, {Shang Tian}",

year = "2004",

month = nov,

language = "English",

pages = "1301--1303",

note = "2004 AIChE Annual Meeting ; Conference date: 07-11-2004 Through 12-11-2004",

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TY - CONF

T1 - Fabrication and functionalization of three-dimensional well-defined scaffolds using novel carbon dioxide assisted microfabrication

AU - Yang, Yong

AU - Basu, Shubhayu

AU - Lee, L. James

AU - Yang, Shang Tian

PY - 2004/11

Y1 - 2004/11

N2 - The construction of 3D scaffolds with well-defined microstructure using a biologically benign carbon dioxide assisted microfabrication (CAMF) was discussed. Astrocytes were cultured in three dimensions in the poly(DL-lactide-co-glycolide) (PLGA) scaffolds and in two dimensions on PLGA films comparison. Low pressure CO 2 was introduced to increase the free volume among the polymer chains. The results show that the scaffold can support cell densities as high as 2.8×10 7 - 5.0×10 7 cells/ml of the scaffold volume.

AB - The construction of 3D scaffolds with well-defined microstructure using a biologically benign carbon dioxide assisted microfabrication (CAMF) was discussed. Astrocytes were cultured in three dimensions in the poly(DL-lactide-co-glycolide) (PLGA) scaffolds and in two dimensions on PLGA films comparison. Low pressure CO 2 was introduced to increase the free volume among the polymer chains. The results show that the scaffold can support cell densities as high as 2.8×10 7 - 5.0×10 7 cells/ml of the scaffold volume.

UR - http://www.scopus.com/inward/record.url?scp=22544457515&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:22544457515

SP - 1301

EP - 1303

T2 - 2004 AIChE Annual Meeting

Y2 - 7 November 2004 through 12 November 2004

ER -

Fabrication and functionalization of three-dimensional well-defined scaffolds using novel carbon dioxide assisted microfabrication

Abstract

Conference

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