ESI MS for Microsized Bioparticles

Abdil Ozdemir; Jung Lee Lin; Mustafa Gulfen; Szu Hsueh Lai; Chun Jen Hsiao; Nelson Chen; Chung Hsuan Chen

doi:10.1021/acs.analchem.7b02937

ESI MS for Microsized Bioparticles

Abdil Ozdemir, Jung Lee Lin, Mustafa Gulfen, Szu Hsueh Lai, Chun Jen Hsiao, Nelson Chen, Chung Hsuan Chen^*

^*Corresponding author for this work

Department of Electrical and Computer Engineering

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

An ESI ion trap mass spectrometer was designed for high-throughput and rapid mass analysis of large bioparticles. Mass calibration of the instrument was performed using commercially available polystyrene (PS) microparticles with a size comparable to cancer cells. Different sizes of MCF-7 breast cancer cells (8 to 15 μm) were used in this study. The masses of different cancer cells were measured. This system allows for the analysis of all types of particles.

Original language	American English
Pages (from-to)	13195-13202
Number of pages	8
Journal	Analytical chemistry
Volume	89
Issue number	24
DOIs	https://doi.org/10.1021/acs.analchem.7b02937
State	Published - 19 Dec 2017

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10.1021/acs.analchem.7b02937

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abstract = "An ESI ion trap mass spectrometer was designed for high-throughput and rapid mass analysis of large bioparticles. Mass calibration of the instrument was performed using commercially available polystyrene (PS) microparticles with a size comparable to cancer cells. Different sizes of MCF-7 breast cancer cells (8 to 15 μm) were used in this study. The masses of different cancer cells were measured. This system allows for the analysis of all types of particles.",

author = "Abdil Ozdemir and Lin, {Jung Lee} and Mustafa Gulfen and Lai, {Szu Hsueh} and Hsiao, {Chun Jen} and Nelson Chen and Chen, {Chung Hsuan}",

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AU - Ozdemir, Abdil

AU - Lin, Jung Lee

AU - Gulfen, Mustafa

AU - Lai, Szu Hsueh

AU - Hsiao, Chun Jen

AU - Chen, Nelson

AU - Chen, Chung Hsuan

PY - 2017/12/19

Y1 - 2017/12/19

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AB - An ESI ion trap mass spectrometer was designed for high-throughput and rapid mass analysis of large bioparticles. Mass calibration of the instrument was performed using commercially available polystyrene (PS) microparticles with a size comparable to cancer cells. Different sizes of MCF-7 breast cancer cells (8 to 15 μm) were used in this study. The masses of different cancer cells were measured. This system allows for the analysis of all types of particles.

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ESI MS for Microsized Bioparticles

Abstract

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