Ein modell zur einteilung des fibromyalgiesyndroms

Translated title of the contribution: Subgroups of fibromyalgia

W. Müller, M. Schneider, T. Joos, Hsin-Yun Hsu, T. Stratz*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


As has been shown by a number of working groups, primary fibromyalgia syndrome does not represent a single clinical entity. It is possible to distinguish between a subgroup with high pain sensitivity and no associated psychiatric condition, a second subgroup characterized by depression and concomitant pain symptoms associated with fibromyalgia syndrome, and a third group with somatoform pain disorder of the fibromyalgia type. Bland inflammatory processes must be considered as the cause in the first group, while depression is the underlying reason for the development of pain in the second group. In the third group, serious previous or still existing psychological problems or also insufficient coping with illness symptoms must be regarded as the reason for pain chronification. Group 1 benefits from a blocking of the 5-HT3 receptors by means of tropisetron, for example. This not only affects pain chronification but also the inflammatory process itself. Group 2 needs antidepressant treatment, whereas the focus should be on psychotherapy is group 3. Groups 1 and 2 will also profit from multimodal physical treatment programs; to a certain extent this applies to group 3 as well. So-called mixed types require a combination of therapeutic measures.

Translated title of the contributionSubgroups of fibromyalgia
Original languageGerman
Pages (from-to)424-429
Number of pages6
Issue number5
StatePublished - 1 Sep 2007


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