Effects of far-infrared radiation on heart rate variability and central manifestations in healthy subjects: a resting-fMRI study

Yii Jeng Lin; Yen Ying Kung; Wen Jui Kuo; David M. Niddam; Chou Ming Cheng; Chih Che Chou; Tzu Chen Yeh; Jen Chuen Hsieh; Jen Hwey Chiu

doi:10.1007/s10103-014-1662-9

Effects of far-infrared radiation on heart rate variability and central manifestations in healthy subjects: a resting-fMRI study

Yii Jeng Lin, Yen Ying Kung, Wen Jui Kuo, David M. Niddam, Chou Ming Cheng, Chih Che Chou, Tzu Chen Yeh, Jen Chuen Hsieh, Jen Hwey Chiu^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The aim of this study was to investigate the autonomic responses and central manifestations by peripheral FIR stimulation. Ten subjects (mean ± SD age 26.2 ± 3.52 years) received FIR stimulation at left median nerve territory for 40 min. Electrocardiograph was continuously recorded and heart rate variability (HRV) were analyzed. By using a 3 T-MRI scanner, three sessions of resting-state functional magnetic resonance images (fMRI) were acquired, namely, before (baseline-FIR), immediately after (IA-FIR) and 15 min after FIR was turned off (Post-FIR). The fractional amplitude of low-frequency (0.01-0.08 Hz) fluctuation (fALFF) of each session to evaluate the intensity of resting-brain activity in each session was analyzed. Our results showed that FIR stimulation induced significant HRV responses such as an increasing trend of nLF and LF/HF ratio, while FIR increased fALFF in right superior front gyrus, middle frontal gyrus and decreased the resting brain activity at fusiform gyrus, extrastriae cortex, inferior temporal gyrus and middle temporal gyrus, especially 15 min after FIR was turned off. We conclude that the central manifestation and the autonomic responses are prominent during and after FIR stimulation, which provide important mechanistic explanation on human disorder treated by such energy medicine.

Original language	English
Pages (from-to)	295-301
Number of pages	7
Journal	Lasers in Medical Science
Volume	30
Issue number	1
DOIs	https://doi.org/10.1007/s10103-014-1662-9
State	Published - Jan 2014

Keywords

Far-infrared radiation
fMRI
Heart rate variability
Resting state network

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title = "Effects of far-infrared radiation on heart rate variability and central manifestations in healthy subjects: a resting-fMRI study",

abstract = "The aim of this study was to investigate the autonomic responses and central manifestations by peripheral FIR stimulation. Ten subjects (mean ± SD age 26.2 ± 3.52 years) received FIR stimulation at left median nerve territory for 40 min. Electrocardiograph was continuously recorded and heart rate variability (HRV) were analyzed. By using a 3 T-MRI scanner, three sessions of resting-state functional magnetic resonance images (fMRI) were acquired, namely, before (baseline-FIR), immediately after (IA-FIR) and 15 min after FIR was turned off (Post-FIR). The fractional amplitude of low-frequency (0.01-0.08 Hz) fluctuation (fALFF) of each session to evaluate the intensity of resting-brain activity in each session was analyzed. Our results showed that FIR stimulation induced significant HRV responses such as an increasing trend of nLF and LF/HF ratio, while FIR increased fALFF in right superior front gyrus, middle frontal gyrus and decreased the resting brain activity at fusiform gyrus, extrastriae cortex, inferior temporal gyrus and middle temporal gyrus, especially 15 min after FIR was turned off. We conclude that the central manifestation and the autonomic responses are prominent during and after FIR stimulation, which provide important mechanistic explanation on human disorder treated by such energy medicine.",

keywords = "Far-infrared radiation, fMRI, Heart rate variability, Resting state network",

author = "Lin, {Yii Jeng} and Kung, {Yen Ying} and Kuo, {Wen Jui} and Niddam, {David M.} and Cheng, {Chou Ming} and Chou, {Chih Che} and Yeh, {Tzu Chen} and Hsieh, {Jen Chuen} and Chiu, {Jen Hwey}",

note = "Publisher Copyright: {\textcopyright} 2014, Springer-Verlag London.",

year = "2014",

month = jan,

doi = "10.1007/s10103-014-1662-9",

language = "English",

volume = "30",

pages = "295--301",

journal = "Lasers in Medical Science",

issn = "0268-8921",

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T1 - Effects of far-infrared radiation on heart rate variability and central manifestations in healthy subjects

T2 - a resting-fMRI study

AU - Lin, Yii Jeng

AU - Kung, Yen Ying

AU - Kuo, Wen Jui

AU - Niddam, David M.

AU - Cheng, Chou Ming

AU - Chou, Chih Che

AU - Yeh, Tzu Chen

AU - Hsieh, Jen Chuen

AU - Chiu, Jen Hwey

PY - 2014/1

Y1 - 2014/1

N2 - The aim of this study was to investigate the autonomic responses and central manifestations by peripheral FIR stimulation. Ten subjects (mean ± SD age 26.2 ± 3.52 years) received FIR stimulation at left median nerve territory for 40 min. Electrocardiograph was continuously recorded and heart rate variability (HRV) were analyzed. By using a 3 T-MRI scanner, three sessions of resting-state functional magnetic resonance images (fMRI) were acquired, namely, before (baseline-FIR), immediately after (IA-FIR) and 15 min after FIR was turned off (Post-FIR). The fractional amplitude of low-frequency (0.01-0.08 Hz) fluctuation (fALFF) of each session to evaluate the intensity of resting-brain activity in each session was analyzed. Our results showed that FIR stimulation induced significant HRV responses such as an increasing trend of nLF and LF/HF ratio, while FIR increased fALFF in right superior front gyrus, middle frontal gyrus and decreased the resting brain activity at fusiform gyrus, extrastriae cortex, inferior temporal gyrus and middle temporal gyrus, especially 15 min after FIR was turned off. We conclude that the central manifestation and the autonomic responses are prominent during and after FIR stimulation, which provide important mechanistic explanation on human disorder treated by such energy medicine.

AB - The aim of this study was to investigate the autonomic responses and central manifestations by peripheral FIR stimulation. Ten subjects (mean ± SD age 26.2 ± 3.52 years) received FIR stimulation at left median nerve territory for 40 min. Electrocardiograph was continuously recorded and heart rate variability (HRV) were analyzed. By using a 3 T-MRI scanner, three sessions of resting-state functional magnetic resonance images (fMRI) were acquired, namely, before (baseline-FIR), immediately after (IA-FIR) and 15 min after FIR was turned off (Post-FIR). The fractional amplitude of low-frequency (0.01-0.08 Hz) fluctuation (fALFF) of each session to evaluate the intensity of resting-brain activity in each session was analyzed. Our results showed that FIR stimulation induced significant HRV responses such as an increasing trend of nLF and LF/HF ratio, while FIR increased fALFF in right superior front gyrus, middle frontal gyrus and decreased the resting brain activity at fusiform gyrus, extrastriae cortex, inferior temporal gyrus and middle temporal gyrus, especially 15 min after FIR was turned off. We conclude that the central manifestation and the autonomic responses are prominent during and after FIR stimulation, which provide important mechanistic explanation on human disorder treated by such energy medicine.

KW - Far-infrared radiation

KW - fMRI

KW - Heart rate variability

KW - Resting state network

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Effects of far-infrared radiation on heart rate variability and central manifestations in healthy subjects: a resting-fMRI study

Abstract

Keywords

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