@article{2b044667a59c460e8f14638f15be54a4,
title = "Effects of anti-triadin antibody on Ca2+ release from sarcoplasmic reticulum",
abstract = "The monoclonal antibody, mAb GE 4.90, raised against triadin, a 95 kDa protein of sarcoplasmic reticulum (SR), inhibits the slow phase of Ca2+ release from SR following depolarization of the T-tubule moiety of the triad. The antibody has virtually no effect on the fast phase of depolarization-induced Ca2+ release nor on caffeine-induced Ca2+ release. Since the slow phase of depolarization-induced Ca2+ release is also inhibited by dihydropyridines (DHP), these results suggest that triadin may be involved in the functional coupling between the DHP receptor and the SR Ca2+ channel.",
keywords = "Ca release, Excitation-contraction coupling, Sarcoplasmic reticulum, Triadin",
author = "Brandt, {Neil R.} and Caswell, {Anthony H.} and Brunschwig, {J. P.} and Kang, {Jaw Jou} and Bozena Antoniu and Noriaki Ikemoto",
note = "Funding Information: Acknowledgelnents: We thank Mr. Adiv J. Zcind for his kind help in atomic absorption assays of sodium, and Dr. John Gergely for his comments on the manuscript. This work was supported by grants froin the NIH (AR 21601, AR 16922), Amerimn Heart Association, Florida Affiliate, and the Muscular Dystrophy Association. This work was done during the tenure of a research fellowship from the Amerigan Heart Association, Massachusetts Affiliate Inc. to J.-J.K.",
year = "1992",
month = mar,
day = "2",
doi = "10.1016/0014-5793(92)80100-U",
language = "English",
volume = "299",
pages = "57--59",
journal = "FEBS Letters",
issn = "0014-5793",
publisher = "Wiley-Blackwell",
number = "1",
}