Dynamic gadolinium-enhanced MR imaging of recurrent inverted papilloma

P. H. Lai*, H. B. Pan, C. F. Yang, M. T. Wu, S. T. Chu, L. P. Ger

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


To evaluate the usefulness of dynamic Gd-enhanced MR imaging in distinguishing recurrent inverted papilloma (IP) from postoperative changes. Ten patients with 13 surgical proved lesions were examined. T1-weighted (pre- and postcontrast), proton-density, and T2-weighted spin-echo images were evaluated. A total of nine dynamic FSE (fast spin-echo) images were obtained at 0, 5, 30, 60, 90, 120, 150, 180, and 300 seconds after bolus Gd-DTPA injection. Signal-time curves were obtained from dynamic scan. Reading of the T2-weighted images yielded a sensitivity of 75%, a specificity of 80%, and an accuracy of 77%. The contrast T1-weighted studies yielded a sensitivity of 63%, a specificity of 60%, and an accuracy of 67%. With a relative signal increase (RSI) of 2.0 or higher, a 60-second imaging time provided the sensitivity of 87% for the detection of recurrence and a specificity of 80%. There were significant differences in the RSI at 30, 60, 90, 120, 150, and 180 seconds (P < 0.01) between recurrent tumor and postoperative changes. Dynamic MR imaging can increase the diagnostic accuracy in the local recurrence of IP, and help differentiate recurrence and postoperative changes.

Original languageEnglish
Pages (from-to)166-168
Number of pages3
JournalRivista di Neuroradiologia
Issue numberSUPPL. 2
StatePublished - 1999


  • MRI
  • Neoplasms
  • Nose
  • Papilloma


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