Development of a fiber optic biosensor with core-shell nanoparticles

Yu Zheng Su; Huihua Kenny Chiang; Min Wei Hung; Wen Hong Wu; Kuo Cheng Huang

doi:10.1109/NANOMED.2009.5559102

Development of a fiber optic biosensor with core-shell nanoparticles

Yu Zheng Su^*, Huihua Kenny Chiang, Min Wei Hung, Wen Hong Wu, Kuo Cheng Huang

^*Corresponding author for this work

Department of Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

We report the development of core-shell nanoparticles with the silver core and SiO₂ shell for potential applications in fiber optic biosensor. The fluorescence intensity of the fluorescence probe (Fluorescein isothiocyanate, FITC) doped core-shell nanoparticles was approximately 50-fold higher than that without core-shell nanoparticles doping. In addition, four different kinds of organic solvents are used in this study and found to have influence on the fluorescence intensity from 1.3 to over 100 times. We conclude that core-shell nanoparticles have capability to enhance the fiber optic sensing through amplifying fluorescence intensity and expect that their potential applications are used in a variety of biological applications.

Original language	English
Title of host publication	2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009
Pages	129-132
Number of pages	4
DOIs	https://doi.org/10.1109/NANOMED.2009.5559102
State	Published - 2009
Event	2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009 - Tainan, Taiwan Duration: 18 Oct 2009 → 21 Oct 2009

Publication series

Name	2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009

Conference

Conference	2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009
Country/Territory	Taiwan
City	Tainan
Period	18/10/09 → 21/10/09

Keywords

Biosensor
Fluorescence
Metal-enhanced fluorescence
Nanoparticles

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10.1109/NANOMED.2009.5559102

Cite this

Su, Y. Z., Chiang, H. K., Hung, M. W., Wu, W. H., & Huang, K. C. (2009). Development of a fiber optic biosensor with core-shell nanoparticles. In 2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009 (pp. 129-132). [5559102] (2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009). https://doi.org/10.1109/NANOMED.2009.5559102

@inproceedings{10711b9b107c421b8c02b41426557162,

title = "Development of a fiber optic biosensor with core-shell nanoparticles",

abstract = "We report the development of core-shell nanoparticles with the silver core and SiO2 shell for potential applications in fiber optic biosensor. The fluorescence intensity of the fluorescence probe (Fluorescein isothiocyanate, FITC) doped core-shell nanoparticles was approximately 50-fold higher than that without core-shell nanoparticles doping. In addition, four different kinds of organic solvents are used in this study and found to have influence on the fluorescence intensity from 1.3 to over 100 times. We conclude that core-shell nanoparticles have capability to enhance the fiber optic sensing through amplifying fluorescence intensity and expect that their potential applications are used in a variety of biological applications.",

keywords = "Biosensor, Fluorescence, Metal-enhanced fluorescence, Nanoparticles",

author = "Su, {Yu Zheng} and Chiang, {Huihua Kenny} and Hung, {Min Wei} and Wu, {Wen Hong} and Huang, {Kuo Cheng}",

year = "2009",

doi = "10.1109/NANOMED.2009.5559102",

language = "English",

isbn = "9781424455287",

series = "2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009",

pages = "129--132",

booktitle = "2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009",

note = "2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009 ; Conference date: 18-10-2009 Through 21-10-2009",

}

Su, YZ, Chiang, HK, Hung, MW, Wu, WH & Huang, KC 2009, Development of a fiber optic biosensor with core-shell nanoparticles. in 2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009., 5559102, 2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009, pp. 129-132, 2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009, Tainan, Taiwan, 18/10/09. https://doi.org/10.1109/NANOMED.2009.5559102

Development of a fiber optic biosensor with core-shell nanoparticles. / Su, Yu Zheng; Chiang, Huihua Kenny; Hung, Min Wei et al.
2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009. 2009. p. 129-132 5559102 (2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Chiang, Huihua Kenny

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N2 - We report the development of core-shell nanoparticles with the silver core and SiO2 shell for potential applications in fiber optic biosensor. The fluorescence intensity of the fluorescence probe (Fluorescein isothiocyanate, FITC) doped core-shell nanoparticles was approximately 50-fold higher than that without core-shell nanoparticles doping. In addition, four different kinds of organic solvents are used in this study and found to have influence on the fluorescence intensity from 1.3 to over 100 times. We conclude that core-shell nanoparticles have capability to enhance the fiber optic sensing through amplifying fluorescence intensity and expect that their potential applications are used in a variety of biological applications.

AB - We report the development of core-shell nanoparticles with the silver core and SiO2 shell for potential applications in fiber optic biosensor. The fluorescence intensity of the fluorescence probe (Fluorescein isothiocyanate, FITC) doped core-shell nanoparticles was approximately 50-fold higher than that without core-shell nanoparticles doping. In addition, four different kinds of organic solvents are used in this study and found to have influence on the fluorescence intensity from 1.3 to over 100 times. We conclude that core-shell nanoparticles have capability to enhance the fiber optic sensing through amplifying fluorescence intensity and expect that their potential applications are used in a variety of biological applications.

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KW - Fluorescence

KW - Metal-enhanced fluorescence

KW - Nanoparticles

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Su YZ, Chiang HK, Hung MW, Wu WH, Huang KC. Development of a fiber optic biosensor with core-shell nanoparticles. In 2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009. 2009. p. 129-132. 5559102. (2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, NANOMED 2009). doi: 10.1109/NANOMED.2009.5559102

Development of a fiber optic biosensor with core-shell nanoparticles

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