Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications

Wing Kam Liu; Ashfaq Adnan; Adrian M. Kopacz; Michelle Hallikainen; Dean Ho; Robert Lam; Jessica Lee; Ted Belytschko; George Schatz; Yonhua Tzeng; Young Jin Kim; Seunghyun Baik; Moon Ki Kim; Taesung Kim; Junghoon Lee; Eung Soo Hwang; Seyoung Im; Eiji Osawa; Amanda Barnard; Huan Cheng Chang; Chia-Ching Chang; Eugenio Oñate

doi:10.1007/978-1-4419-0531-4_12

Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications

Wing Kam Liu^*
, Ashfaq Adnan
, Adrian M. Kopacz
, Michelle Hallikainen
, Dean Ho
, Robert Lam
, Jessica Lee
, Ted Belytschko
, George Schatz
, Yonhua Tzeng
, Young Jin Kim
, Seunghyun Baik
, Moon Ki Kim
, Taesung Kim
, Junghoon Lee
, Eung Soo Hwang
, Seyoung Im
, Eiji Osawa
, Amanda Barnard
, Huan Cheng Chang

Chia-Ching Chang, Eugenio Oñate

^*Corresponding author for this work

Department of Biological Science and Technology

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

11 Scopus citations

Abstract

The onset and recurrence of cancer is one of the major biomedical quandaries of our time. Currently, surgically removed tumors often leave behind a residual cancer cell population. As not all cancer cells can be detected to ensure complete tumor removal, systemic and widespread chemotherapy is usually injected into the-bloodstream to attempt to target the remaining cancer cells. This can result in-devastating side effects because the cancer drugs flow freely throughout the bloodstream with a reduced ability to target-specific regions. This treatment kills both healthy and unhealthy cells, and thus the quality of life of cancer patients is significantly reduced.

Original language	English
Title of host publication	Nanodiamonds
Subtitle of host publication	Applications in Biology and Nanoscale Medicine
Publisher	Springer US
Pages	249-284
Number of pages	36
ISBN (Print)	9781441905307
DOIs	https://doi.org/10.1007/978-1-4419-0531-4_12
State	Published - 2010

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1007/978-1-4419-0531-4_12

Cite this

Liu, W. K., Adnan, A., Kopacz, A. M., Hallikainen, M., Ho, D., Lam, R., Lee, J., Belytschko, T., Schatz, G., Tzeng, Y., Kim, Y. J., Baik, S., Kim, M. K., Kim, T., Lee, J., Hwang, E. S., Im, S., Osawa, E., Barnard, A., ... Oñate, E. (2010). Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications. In Nanodiamonds: Applications in Biology and Nanoscale Medicine (pp. 249-284). Springer US. https://doi.org/10.1007/978-1-4419-0531-4_12

@inbook{4eb9488547cd4f2194276b7a61818385,

title = "Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications",

abstract = "The onset and recurrence of cancer is one of the major biomedical quandaries of our time. Currently, surgically removed tumors often leave behind a residual cancer cell population. As not all cancer cells can be detected to ensure complete tumor removal, systemic and widespread chemotherapy is usually injected into the-bloodstream to attempt to target the remaining cancer cells. This can result in-devastating side effects because the cancer drugs flow freely throughout the bloodstream with a reduced ability to target-specific regions. This treatment kills both healthy and unhealthy cells, and thus the quality of life of cancer patients is significantly reduced.",

author = "Liu, \{Wing Kam\} and Ashfaq Adnan and Kopacz, \{Adrian M.\} and Michelle Hallikainen and Dean Ho and Robert Lam and Jessica Lee and Ted Belytschko and George Schatz and Yonhua Tzeng and Kim, \{Young Jin\} and Seunghyun Baik and Kim, \{Moon Ki\} and Taesung Kim and Junghoon Lee and Hwang, \{Eung Soo\} and Seyoung Im and Eiji Osawa and Amanda Barnard and Chang, \{Huan Cheng\} and Chia-Ching Chang and Eugenio O{\~n}ate",

year = "2010",

doi = "10.1007/978-1-4419-0531-4\_12",

language = "English",

isbn = "9781441905307",

pages = "249--284",

booktitle = "Nanodiamonds",

publisher = "Springer US",

address = "美國",

}

Liu, WK, Adnan, A, Kopacz, AM, Hallikainen, M, Ho, D, Lam, R, Lee, J, Belytschko, T, Schatz, G, Tzeng, Y, Kim, YJ, Baik, S, Kim, MK, Kim, T, Lee, J, Hwang, ES, Im, S, Osawa, E, Barnard, A, Chang, HC, Chang, C-C & Oñate, E 2010, Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications. in Nanodiamonds: Applications in Biology and Nanoscale Medicine. Springer US, pp. 249-284. https://doi.org/10.1007/978-1-4419-0531-4_12

TY - CHAP

T1 - Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications

AU - Liu, Wing Kam

AU - Adnan, Ashfaq

AU - Kopacz, Adrian M.

AU - Hallikainen, Michelle

AU - Ho, Dean

AU - Lam, Robert

AU - Lee, Jessica

AU - Belytschko, Ted

AU - Schatz, George

AU - Tzeng, Yonhua

AU - Kim, Young Jin

AU - Baik, Seunghyun

AU - Kim, Moon Ki

AU - Kim, Taesung

AU - Lee, Junghoon

AU - Hwang, Eung Soo

AU - Im, Seyoung

AU - Osawa, Eiji

AU - Barnard, Amanda

AU - Chang, Huan Cheng

AU - Chang, Chia-Ching

AU - Oñate, Eugenio

PY - 2010

Y1 - 2010

N2 - The onset and recurrence of cancer is one of the major biomedical quandaries of our time. Currently, surgically removed tumors often leave behind a residual cancer cell population. As not all cancer cells can be detected to ensure complete tumor removal, systemic and widespread chemotherapy is usually injected into the-bloodstream to attempt to target the remaining cancer cells. This can result in-devastating side effects because the cancer drugs flow freely throughout the bloodstream with a reduced ability to target-specific regions. This treatment kills both healthy and unhealthy cells, and thus the quality of life of cancer patients is significantly reduced.

AB - The onset and recurrence of cancer is one of the major biomedical quandaries of our time. Currently, surgically removed tumors often leave behind a residual cancer cell population. As not all cancer cells can be detected to ensure complete tumor removal, systemic and widespread chemotherapy is usually injected into the-bloodstream to attempt to target the remaining cancer cells. This can result in-devastating side effects because the cancer drugs flow freely throughout the bloodstream with a reduced ability to target-specific regions. This treatment kills both healthy and unhealthy cells, and thus the quality of life of cancer patients is significantly reduced.

UR - https://www.scopus.com/pages/publications/84861662465

U2 - 10.1007/978-1-4419-0531-4_12

DO - 10.1007/978-1-4419-0531-4_12

M3 - Chapter

AN - SCOPUS:84861662465

SN - 9781441905307

SP - 249

EP - 284

BT - Nanodiamonds

PB - Springer US

ER -

Design of nanodiamond based drug delivery patch for cancer therapeutics and imaging applications

Abstract

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