Design of multi-channel monopolar biphasic stimulator for implantable biomedical applications

Chia Chi Hsieh, Ming-Dou Ker

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

8 Scopus citations

Abstract

Neuro-stimulators have been widely used in neural disorder control. This work presents a four-channel stimulator with adjustable positive and negative stimulus voltage from 0.5V to 8V. In the proposed stimulator, circuit operation with negative voltage has been successfully realized in a 0.25-μm 2.5-V/5-V/12-V CMOS process with the grounded p-type substrate, and without suffering the p-n junction breakdown or electrical overstress issues. The proposed stimulator has been also practically verified with in-vivo animal test. By integrating the stimulator circuit with other circuit blocks together, the close-loop neuromodulation treatment can be implemented by an implantable system-on-chip (SoC) with low-power consumption.

Original languageEnglish
Title of host publication2018 IEEE 61st International Midwest Symposium on Circuits and Systems, MWSCAS 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages49-52
Number of pages4
ISBN (Electronic)9781538673928
DOIs
StatePublished - 5 Aug 2019
Event61st IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2018 - Windsor, Canada
Duration: 5 Aug 20188 Aug 2018

Publication series

NameMidwest Symposium on Circuits and Systems
Volume2018-August
ISSN (Print)1548-3746

Conference

Conference61st IEEE International Midwest Symposium on Circuits and Systems, MWSCAS 2018
Country/TerritoryCanada
CityWindsor
Period5/08/188/08/18

Keywords

  • In-vivo animal test
  • Neural stimulation
  • SoC integration
  • Stimulator

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