Cyanine scaffold as dual-channel colorimetric and near-infrared emitting probe for sensitive detection of phosgene in environment and live cell

Natarajan Vijay; Shu Pao Wu; Sivan Velmathi

doi:10.1016/j.snb.2022.132567

Cyanine scaffold as dual-channel colorimetric and near-infrared emitting probe for sensitive detection of phosgene in environment and live cell

Natarajan Vijay, Shu Pao Wu, Sivan Velmathi^*

^*Corresponding author for this work

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The detection of chemical warfare agent (CWA's) in real time is obligatory in order to ease the threatening effect of these acute toxic agents to humankind. Herein, firstly we attempted, reversible, colorimetric, and fluorescent detection of phosgene in aqueous system succinctly described based on cyanine scaffold. Rapid and dual response of the probe was constructively employed to monitor the phosgene in the environment by strip test and soil analysis. The probe provides up to ppb (LOD of 0.08 ppb) level detection of phosgene with distinct color and fluorescence change. The turn-on near-infrared (NIR) fluorescence response bring in to play effectively to image trace level phosgene in live cell by fluorescent bio-imaging application.

Original language	English
Article number	132567
Journal	Sensors and Actuators, B: Chemical
Volume	371
DOIs	https://doi.org/10.1016/j.snb.2022.132567
State	Published - 15 Nov 2022

Keywords

Fluorescent bio-imaging
NIR emission
Phosgene
Soil analysis
Strip test

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10.1016/j.snb.2022.132567

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title = "Cyanine scaffold as dual-channel colorimetric and near-infrared emitting probe for sensitive detection of phosgene in environment and live cell",

abstract = "The detection of chemical warfare agent (CWA's) in real time is obligatory in order to ease the threatening effect of these acute toxic agents to humankind. Herein, firstly we attempted, reversible, colorimetric, and fluorescent detection of phosgene in aqueous system succinctly described based on cyanine scaffold. Rapid and dual response of the probe was constructively employed to monitor the phosgene in the environment by strip test and soil analysis. The probe provides up to ppb (LOD of 0.08 ppb) level detection of phosgene with distinct color and fluorescence change. The turn-on near-infrared (NIR) fluorescence response bring in to play effectively to image trace level phosgene in live cell by fluorescent bio-imaging application.",

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AU - Vijay, Natarajan

AU - Wu, Shu Pao

AU - Velmathi, Sivan

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AB - The detection of chemical warfare agent (CWA's) in real time is obligatory in order to ease the threatening effect of these acute toxic agents to humankind. Herein, firstly we attempted, reversible, colorimetric, and fluorescent detection of phosgene in aqueous system succinctly described based on cyanine scaffold. Rapid and dual response of the probe was constructively employed to monitor the phosgene in the environment by strip test and soil analysis. The probe provides up to ppb (LOD of 0.08 ppb) level detection of phosgene with distinct color and fluorescence change. The turn-on near-infrared (NIR) fluorescence response bring in to play effectively to image trace level phosgene in live cell by fluorescent bio-imaging application.

KW - Fluorescent bio-imaging

KW - NIR emission

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KW - Soil analysis

KW - Strip test

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Cyanine scaffold as dual-channel colorimetric and near-infrared emitting probe for sensitive detection of phosgene in environment and live cell

Abstract

Keywords

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