Composition of phenolic compounds and antioxidant attributes of Cyclea gracillima Diels extracts

Jau Tien Lin, Shih Chuan Liu, Li Chun Kuo, Deng Jye Yang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Cyclea gracillima Diels is a Taiwanese native medicinal herb. However, there are currently few relevant reports on its biochemical activity. In this study, the antioxidant attributes of the ethanol and hot water extracts of this herb were assayed using in vitro models, including the following: 2,2-diphenyl-1-(2,4,6-trinitrophenyl)-hydrazyl radical scavenging, Trolox equivalent antioxidant capacity, reducing power, and chelating ferrous ions. The following biochemical models were also assayed: inhibition of human low density lipoprotein oxidation, inhibition of human erythrocyte hemolysis, and scavenging oxygen radicals in human blood. The composition and content of flavonoids and phenolic acids in these extracts were also analyzed. The results showed that these extracts with high polyphenol levels presented remarkable antioxidant effects in all assays, especially when extracted with ethanol. Six phenolic acids (mainly ferulic acid, sinapic acid, and syringic acid) and 12 flavonoids (mainly narigenin, myricetin, naringin, and apigenin) were found in these extracts.

Original languageEnglish
Pages (from-to)193-200
Number of pages8
JournalJournal of Food and Drug Analysis
Issue number1
StatePublished - Jan 2018


  • antioxidant
  • Cyclea gracillima Diels
  • flavonoid
  • phenol
  • phenolic acid


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