Compact surface plasmon resonance biosensor utilizing an injection-molded prism

How Foo Chen*, Chih Han Chen, Yun Hsiang Chang, Hsin Yuan Chuang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Targeting at a low cost and accessible diagnostic device in clinical practice, a compact surface plasmon resonance (SPR) biosensor with a large dynamic range in high sensitivity is designed to satisfy commercial needs in food safety, environmental bio-pollution monitoring, and fast clinical diagnosis. The core component integrates an optical coupler, a sample-loading plate, and angle-tuning reflectors is injection-molded as a free-from prism made of plastic optics. This design makes a matching-oil-free operation during operation. The disposability of this low-cost component ensures testing or diagnosis without cross contamination in bio-samples.

Original languageEnglish
Title of host publicationAdvanced Environmental, Chemical, and Biological Sensing Technologies XIII
EditorsTuan Vo-Dinh, Robert A. Lieberman, Gunter G. Gauglitz
PublisherSPIE
ISBN (Electronic)9781510601031
DOIs
StatePublished - 2016
EventAdvanced Environmental, Chemical, and Biological Sensing Technologies XIII - Baltimore, United States
Duration: 17 Apr 201619 Apr 2016

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume9862
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceAdvanced Environmental, Chemical, and Biological Sensing Technologies XIII
Country/TerritoryUnited States
CityBaltimore
Period17/04/1619/04/16

Keywords

  • Biological sensing
  • free form optical design
  • microscope compatibility
  • phase interrogation
  • polymer molding
  • sensor
  • Surface plasmon resonance
  • tunable excitation angle

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