@inproceedings{a5b9c234738740cd826178bd6a55631e,
title = "Color doppler sonographic evaluation of peak systolic velocity and pulsatility index in artery after pulsed HIFU exposure",
abstract = "The objective of current study was to investigate the functional changes in arteries induced by pulsed-HIFU with or without microbubbles. Sonication was applied at an ultrasound frequency of 1 MHz with a burst length of 50ms and a repetition frequency of 1 Hz. The duration of the whole sonication was 6s. The abdominal aortas of Sprague-Dawley rats were surgically exposed and sonicated with pulsed HIFU; the pulsed HIFU beam was aimed using color images of the blood flow. There was no obvious normalized peak systolic velocity (PSV) change at various acoustic powers of pulsed-HIFU exposure in the absence of ultrasound contrast agent (UCA). However, the normalized PSV change induced by pulsed-HIFU decreased with the injected dose of UCA at acoustic powers. At this time, the normalized pulsatility index (PI) change in the vessel subjected to pulsed-HIFU increased in proportion to UCA dose. Additional research is needed to investigate the detailed mechanical effects of pulsed-HIFU exposure on blood flow and the structure of vessel walls.",
keywords = "Blood flow velocity, Peak systolic velocity, Pulsatility index, Pulsed HIFU",
author = "Yang, {Feng Yi} and Chiu, {Wei Hsiu} and Yeh, {Chi Fang}",
year = "2011",
doi = "10.1063/1.3607919",
language = "English",
isbn = "9780735409170",
series = "AIP Conference Proceedings",
pages = "283--288",
booktitle = "10th International Symposium on Therapeutic Ultrasound, ISTU 2010",
note = "10th International Symposium on Therapeutic Ultrasound, ISTU 2010 ; Conference date: 09-06-2010 Through 12-06-2010",
}