Colonic transit disorders in systemic sclerosis

S. J. Wang*, J. L. Lan, D. Y. Chen, Y. H. Chen, T. Y. Hsieh, W. Y. Lin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Systemic sclerosis (SS) alters smooth muscle function throughout the gastrointestinal tract, the oesophagus being the segment most often involved. Involvement of the colon, though less common, may lead to life-threatening complications. We studied 23 unselected patients with SS and 20 age-matched healthy controls using radionuclide colon transit studies. The geometric centre (GC) at 4 and 24 hours was used to summarise overall transit in the colon. In patients with SS, colon transit was delayed (GC4: 0.39 ± 0.36 vs 0.85 ± 0.45; P=0.001) (GC24: 1.68 ± 0.9 vs 2.58 ± 1.08; P=0.006). These findings suggest that delayed colon transit is common in patients with SS.

Original languageEnglish
Pages (from-to)251-254
Number of pages4
JournalClinical Rheumatology
Issue number4
StatePublished - 2001


  • Charcoal
  • Colon
  • Scintigraphy
  • Systemic sclerosis


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