Chiral Structured Illumination Microscopy

Shiang-Yu Huang, Jiwei Zhang, Christian Karras, Ronny Forster, Rainer Heintzmann, Jer-Shing Huang

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

We propose a chiral imaging modality based on optical chirality engineering, fluorescence-detected circular dichroism, and structured illumination microscopy. In this method, the optical chirality of the illumination is structured and the circular dichroism dependent fluorescence is detected. With image reconstruction, the spatial distribution of the chiral domains can be obtained at subdiffraction-limited resolution. We theoretically demonstrate this method and discuss the feasibility of using an optical chirality engineering approach based on far-field optics.

Original languageEnglish
Pages (from-to)130-134
Number of pages5
JournalACS Photonics
Volume8
Issue number1
DOIs
StatePublished - 20 Jan 2021

Keywords

  • chiral imaging
  • structured illumination microscopy
  • optical chirality
  • circular dichroism
  • super resolution
  • CIRCULAR-DICHROISM SPECTROSCOPY
  • PLANE-WAVES
  • POLYFLUORENE
  • GENERATION
  • EXCITATION
  • RESOLUTION

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